Unsatisfactory results of a drug resistant epilepsy surgical treatment: reasons analysis and treatment optimization way
https://doi.org/10.18705/2311-4495-2018-5-4-60-68
Abstract
The relevance of the studied problem was caused by high prevalence of drug resistant epilepsy, an increased structural epilepsy detection and extension indications for a surgical treatment.
The purpose of article consisted in a research of the reasons of low efficiency of epilepsy surgical treatment in adult population with a cross-disciplinary approach position.
Material and methods. The leading approach was the retrospective open research of the failure factors at 14 patiens.
Results. It was revealed unsatisfactory result of epilepsy surgical treatment was caused by a complex of the reasons. The disease features have been the main reason for a failure in 100% of cases, additional reasons: irrational pharmacotherapy -in 86%, the surgical reasons — in 36% of cases.
Conclusions. The unsatisfactory result of epilepsy surgical treatment was caused by a complex of the reasons. Cross-disciplinary approach to a problem, improvement of the epilepsy managment, further researches are required. Materials of article can be useful for the personified approach at surgical treatment of epilepsy.
About the Authors
G. V. Odintsova
Polenov Russian Scienific Research Institute of Neurosurgery
Russian Federation
Competing Interests:
Russian Federation
Galina V. Odintsova - MD, PhD.
Mayakovskaya str. 12, Saint Petersburg, 191014
Competing Interests:
No conflict of interest
M. V. Aleksandrov
Polenov Russian Scienific Research Institute of Neurosurgery
Russian Federation
Competing Interests:
Russian Federation
Mikhail V. Aleksandrov - MD, Dr. Sci., prof.
Mayakovskaya str. 12, Saint Petersburg, 191014
Competing Interests:
No conflict of interest
A. U. Ulitin
Polenov Russian Scienific Research Institute of Neurosurgery
Russian Federation
Competing Interests:
Russian Federation
Aleksey U. Ulitin - MD, Dr. Sci., the head.
Mayakovskaya str. 12, Saint Petersburg, 191014
Competing Interests:
No conflict of interest
V. G. Nezdorovina
Polenov Russian Scienific Research Institute of Neurosurgery
Russian Federation
Competing Interests:
Russian Federation
MD, PhD.
Mayakovskaya str. 12, Saint Petersburg, 191014
Competing Interests:
No conflict of interest
A. A. Chuchlovin
Polenov Russian Scienific Research Institute of Neurosurgery
Russian Federation
Competing Interests:
Russian Federation
Aleksandr A. Chuchlovin - MD, PhD.
Mayakovskaya str. 12, Saint Petersburg, 191014
Competing Interests:
No conflict of interest
А. V. Koloteva
Polenov Russian Scienific Research Institute of Neurosurgery
Russian Federation
Competing Interests:
Russian Federation
Anna V. Koloteva – intern.
Mayakovskaya str. 12, Saint Petersburg, 191014
Competing Interests:
No conflict of interest
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Review
For citations:
Odintsova G.V., Aleksandrov M.V., Ulitin A.U., Nezdorovina V.G., Chuchlovin A.A., Koloteva А.V. Unsatisfactory results of a drug resistant epilepsy surgical treatment: reasons analysis and treatment optimization way. Translational Medicine. 2018;5(4):60-68. (In Russ.) https://doi.org/10.18705/2311-4495-2018-5-4-60-68
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