Preview

Трансляционная медицина

Расширенный поиск

Оценка субклинического поражения сосудов на популяционном уровне

https://doi.org/10.18705/2311-4495-2014-0-2-26-38

Полный текст:

Аннотация

В настоящее время одной из наиболее эффективных стратегий профилактики признана стратегия высокого риска. В рамках такой стратегии первичная профилактика сердечно-сосудистых заболеваний направлена на оценку риска с последующим выбором стратегии превентивных мер и лечения. Существующие алгоритмы оценки с помощью традиционных факторов риска приводят к формированию многочисленной группы лиц промежуточного риска, которая может включать в себя долю лиц высокого риска, требующих более агрессивной терапевтической тактики. Одним из важнейших дополнительных методов обследования, помогающих в стратификации риска, является оценка субклинического поражения артерий, который также принято называть визуализирующими биомаркерами риска. Обсуждаемые в обзоре методы диагностики органных поражений имеют свои достоинства и недостатки, разную доказательную базу и экономическую эффективность, что приводит к отсутствию единых алгоритмов и рекомендаций. Наличие большого количества обсуждаемых маркеров обусловлено, с одной стороны, востребованностью разработки критериев для активной первичной профилактики, с другой стороны - необходимостью учета экономических затрат при скрининге на уровне популяции. Продолжается поиск визуализирующих биомаркеров, которые, с учетом оптимального соотношения чувствительности, специфичности и стоимости, смогут быть использованы для скрининга на популяционном уровне.

Об авторах

Асият Сайгидовна Алиева
ФГБУ «Федеральный медицинский исследовательский центр имени В.А. Алмазова» Минздрава России
Россия


Оксана Петровна Ротарь
ФГБУ «Федеральный медицинский исследовательский центр имени В.А. Алмазова» Минздрава России
Россия


Александра Олеговна Конради
ФГБУ «Федеральный медицинский исследовательский центр имени В.А. Алмазова» Минздрава России
Россия


Список литературы

1. Franco O.H., Karnik K., Osborne G., Ordovas J.M. et al. Changing course in ageing research: The healthy ageing phenotype // Maturitas. - 2009. - Vol. 20, № 63, Supp. 1. - P. 13-19.

2. Najjar S.S., Scuteri A., Lakatta E.G. Arterial aging: is it an immutable cardiovascular risk factor? // Hypertension. - 2005. - Vol. 46. - P. 454-462.

3. Nilsson P.M. Hemodynamic Aging as the Consequence of Structural Changes Associated with Early Vascular Aging (EVA) // Aging Dis. - 2014. - Vol. 1, № 5, Supp. 2. - P. 109-113.

4. Barker D.J.P. The intrauterine origins of cardiovascular disease and obstructive lung disease in adult life // J. R. Coll. Physicians Lond. - 1991. - Vol. 25. - P. 12933.

5. Assmann G., Cullen P., Schulte H. The Munster Heart Study (PROCAM) // European Heart Journal. - 1998. - Vol. 19, Supp. A. - A2-A11.

6. Conroy R.M., Pyörälä K., Fitzgerald A.P. et al. Estimation of ten-year risk of fatal cardiovascular disease in Europe: the SCORE project // European Heart Journal. - 2003. - Vol. 24, № 11. - P. 987-1003.

7. Castelli W.P., Anderson K. A population at risk. Prevalence of high cholesterol levels in hypertensive patients in the Framingham Study // Am. J. Med. - 1986. - Vol. 14, № 80, Supp. 2A. - P. 23-32.

8. Brindle P., Emberson J., Lample F. et al. Predictive accuracy of the Famingham Coronary Risk Score in British Men: prospective cohort study // BMJ. - 2003. - Vol. 327. - P. 1267-1270.

9. Wald N.J., Simmonds M., Morris J.K. Screening for future cardiovascular disease using age alone compared with multiple risk factors and age // PLoS ONE. - 2011. - Vol. 6, № 5. - [Электронный ресурс] doi: 10.1371/journal. pone.0018742

10. Rose G. The Strategy of Preventive Medicine. - Oxford University Press, 1992. - 171 p.

11. Greenland P., Knoll M.D., Stamler J. et al. Major risk factors as antecedents of fatal and nonfatal coronary heart disease events // JAMA. - 2003. - Vol. 290. - P. 891-897.

12. Vasan R.S. Biomarkers of cardiovascular disease: molecular basis and practical considerations // Circulation. - 2006. - Vol. 113. - P. 2335-2362.

13. Wang T.J. Assessing the role of circulating, genetic, and imaging biomarkers in cardiovascular risk prediction // Circulation. - 2011. - Vol. 123. - P. 551-565.

14. Nilsson P., Boutouyrie P., Laurent S. Vascular aging: a tale of EVA and ADAM in cardiovascular risk assessment and prevention // Hypertension. - 2009. - Vol. 54, № 3. - P. 10.

15. Van Bortel L.M., Laurent S., Boutouyrie P. Expert consensus document on the measurement of aortic stiffness in daily practice using carotid-femoral pulse wave velodty // J. Hypertens. - 2012. - Vol. 30, №. 3. - P. 445-448.

16. Newman A.B., Siscovick D.S., Manolio T.A. et al. Cardiovascular Heart Study (CHS) Collaborative Research Group. Ankle-arm index as a marker of atherosclerosis in the Cardiovascular Health Study // Circulation. - 1993. - Vol. 88, № 3. - P. 837-845.

17. Lorenz M.W., Markus H.S., Bots M.L. et al. Prediction of clinical cardiovascular events with carotid intima-media thickness: a systematic review and meta-analysis // Circulation. - 2007. - Vol. 115, № 4. - P. 459-467.

18. Mitchell G.F., Parise H., Benjamin E.J. Changes in arterial stiffness and wave reflection with advanced age in healthy men and women: the Framingham Heart Study // Hypertension. - 2004. - Vol. 43, № 6. - P. 1239-1245.

19. Ross R. Atherosclerosis - an inflammatory disease // N. Engl. J. Med. - 1999. - Vol. 340. - P. 115-126.

20. Nichols W.W. Clinical measurement of arterial stiffness obtained from non-invasive pressure waveforms // Am. J. Hypertens. - 2005. - Vol. 18, № 1, Supp. 2. - P. 3-10.

21. Laurent S., Boutouyrie P., Asmar R. et al. Aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in hypertensive patients // Hypertension. - 2001. - Vol. 37. - P. 1236-1241.

22. Boutouyrie P., Tropeano A.I., Asmar R. et al. Aortic stiffness is an independent predictor of primary coronary events in hypertensive patients: a longitudinal study // Hypertension. - 2002. - Vol. 39. - P. 10-15.

23. Laurent S., Katsahian S., Fassot C. et al. Aortic stiffness is an independent predictor of fatal stroke in essential hypertension // Stroke. - 2003. - Vol. 34. - P. 1203-1206.

24. Mattace-Raso F.U., van der Cammen T.J., Hofman A. et al. Arterial stiffness and risk of coronary heart disease and stroke: the Rotterdam Study // Circulation. - 2006. - Vol. 113. - P. 657-663.

25. Pannier B., Guerin A.P., Marchais S.J. et al. Stiffness of capacitive and conduit arteries: prognostic significance for end-stage renal disease patients // Hypertension. - 2005. - Vol. 45. - P. 592-596.

26. Sehestedt T., Jeppesen J., Hansen T. W. Risk prediction is improved by adding markers of subclinical organ damage to SCORE // Eur. Heart J. - 2010. - Vol. 31, № 7. - P. 883-891.

27. Mitchell G.F., Shih-Jen Hwang, Vasan R.S. et al. Arterial Stiffness and Cardiovascular Events: The Framingham Heart Study // Circulation. - 2010. - Vol. 121. - P. 505-511.

28. Vlachopoulos C., Aznaouridis K., Stefanadis C. Prediction of Cardiovascular Events and All-Cause Mortality With Arterial Stiffness // J. Amer. Coll. Cardiol. - 2010. - Vol. 55, Supp. 13. - P. 1318-1327.

29. Matsuoka O., Otsuka K., Murakami S. et al. Arterial stiffness independently predicts cardiovascular events in an elderly community. - Longitudional Investigation for the Longevity and Aging in Hokkaido County (LILAC) study // Biomed. Pharmacother. - 2005. - Vol. 59, № 2. - P. 40-44.

30. Tomiyama H., Koji Y., Yambe M. et al. Brachial-ankle pulse wave velocity is a simple and independent predictor of prognosis in patients with acute coronary syndrome // Circulation J. - 2005. - Vol. 69. - P. 815-822.

31. Takashima N., Turin T.C., Matsui K. et al. The relationship of brachial-ankle pulse wave velocity to future cardiovascular disease events in the general Japanese population: the Takashima Study // J. Hum. Hypertens. - 2013. - [Электронный ресурс] doi: 10.1038/jhh.2013.103

32. Yamashina A., Tomiyama H., Takeda K. et al. Validity, reproducibility, and clinical significance of noninvasive brachial-ankle pulse wave velocity measurement // Hypertens. Res. - 2002. - Vol. 25. - P. 359-364.

33. Munakata M., Konno S., Miura Y. et al. Prognostic significance of the brachial-ankle pulse wave velocity in patients with essential hypertension: final results of the J-TOPP study // Hypertens. Res. - 2012. - Vol. 35, № 8. - P. 839-842.

34. Cecelja M., Chowienczyk P. Dissociation of aortic pulse wave velocity with risk factors for cardiovascular disease other than hypertension: asystematic review // Hypertension. - 2009. - Vol. 54, № 6. - P. 1328-1336.

35. Shirai K., Song M., Suzuki J. et al. Contradictory effects of β1 and α1 aderenergic receptor blockers on cardio-ankle vascular stiffness index (CAVI) - CAVI independent of blood pressure // J. Atheroscler. Thromb. - 2011. - Vol. 18, № 1. - P. 49-55.

36. Satoh N., Shimatsu A., Kato Y. et al. Evaluation of the cardio-ankle vascular index, a new indicator of arterial stiffness independent of blood pressure, in obesity and metabolic syndrome // Hypertens. Res. - 2008. - Vol. 31, № 10. - P. 1921-1930.

37. Okura T., Watanabe S., Kurata M. et al. Relationship between cardio-ankle vascular index (CAVI) and carotid atherosclerosis in patients with essential hypertension // Hypertens. Res. - 2007. - Vol. 30, № 4. - P. 335-340.

38. Shirai K., Utino J., Otsuka K. et al. A novel blood pressure-independent arterial wall stiffness parameter; cardio-ankle vascular index (CAVI) // J. Atheroscler. Thromb. - 2006. - Vol. 13, № 2. - P. 101-107.

39. Takata М., Shimakura А. Principle role of the Cardio-Ankle Vascular Index in the assessment of Vascular Function // From bench to bedside: CAVI as a novel indicator of vascular function. - 2009. - P. 2-15.

40. Sun C.K. Cardio-ankle vascular index (CAVI) as an indicator of arterial stiffness // Integr. Blood Press Control. - 2013. - Vol. 30, № 6. - P. 27-38.

41. Shoda T. et al. Vascular Pathology Research with pulse wave examination CAVI-VaSera // ME Times. - Tokyo, 2005. - P. 7.

42. Liu H., Saijo Y., Zhang X. et al. Comparative analysis of cardio-ankle vascular index between Japanese and Russians. // Yamaguchi M., Keizo I., Ohuchi N., Osumi N., Sato M., Yamaguchi T., editors. Future Medical Engineering Based on Bionanotechnology: Proceedings of the Final Symposium of the Tohoku University 21st Century Center of Excellence Program. - London: Imperial College Press, 2006. - P. 411-418.

43. Uurtuya S., Taniguchi N., Kotani K. et al. Comparative study of the cardio-ankle vascular index and ankle-brachial index between young Japanese and Mongolian subjects // Hypertens. Res. - 2009. - Vol. 32, № 2. - P. 140-144.

44. Yoshiaki K., Daisuke M., Makoto T. et al. Cardio-Ankle Vascular Index is a predictor of cardiovascular events // Artery Research. - 2011. - Vol. 5. - P. 91-96.

45. Namekata T., Suzuki K., Ishizuka N. et al. Establishing baseline criteria of cardio-ankle vascular index as a new indicator of arteriosclerosis: a cross-sectional study // BMC Cardiovasc. Disord. - 2011. - Vol. 11, № 51. - [Электронный ресурс] doi: 10.1186/1471-2261-11-51

46. Mitchell G.F., Shih-Jen Hwang, Vasan R.S. et al. Arterial Stiffness and Cardiovascular Events The Framingham Heart Study // Circulation. - 2010. - Vol. 121. - P. 505-511.

47. Kubota Y. Predictor of cardiovascular disease - CAVI // CAVI. Now and future. The best solution. - Vol. 1. - P. 38-42.

48. The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2009) // Hypertens. Res. - 2009. - Vol. 32. - P. 4-107.

49. Wong T.Y., Mitchell P. Hypertensive retinopathy // N. Engl. J. Med. - 2004. - Vol. 351. - P. 2310-2317.

50. Van den Born B.J., Hulsman C.A., Hoekstra J.B. et al. Value of routine funduscopy in patients with hypertension: systematic review // BMJ. - 2005. - Vol. 331. - P. 73.

51. Schmieder R.E. Hypertensive retinopathy: a window to vascular remodeling in arterial hypertension // Hypertension. - 2008. - Vol. 51. - P. 43-44.

52. Kotliar K., Hanssen H., Eberhardt K. et al. Retinal pulse wave velocity in young male normotensive and mildly hypertensive subjects // Microcirculation. - 2013. - Vol. 20, № 5. - P. 405-415.

53. Schmermund A., Erbel R. Unstable coronary plaque and its relation to coronary calcium // Circulation. - 2001. - Vol. 104. - P. 1682-1687.

54. Lauer M.S. Elements of danger: the case of medical imaging // N. Engl. J. Med. - 2009. - Vol. 361. - P. 841-843.

55. Stein J.H., Korcarz C.E., Hurst T. et al. Use of Carotid Ultrasound to Identify Subclinical Vascular Disease and Evaluate Cardiovascular Disease Risk: A Consensus Statement from the American Society of Echocardiography Carotid Intima-Media Thickness // J. Am. Soc. Echocardiogr. - 2008. - Vol. 21, № 2. - P. 93-111.

56. Lorenz M.W., Markus H.S., Bots M.L. et al. Prediction of clinical cardiovascular events with carotid intimamedia thickness: a systematic review and meta-analysis // Circulation. - 2007. - Vol. 115, № 4. - P. 459-467.

57. Society of Atherosclerosis Imaging and Prevention Developed in collaboration with the International Atherosclerosis Society. Appropriate use criteria for carotid intima media thickness testing // Atherosclerosis. - 2011. - Vol. 214, № 1. - P. 43-46.

58. O’Leary D.H., Polak J.F., Kronmal R.A. et al. Carotid artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults. Cardiovascular Health Study Collaborative Research Group // N. Engl. J. Med. - 1999. - Vol. 340, № 1. - P. 14-22.

59. Bots M.L., Hoes A.W., Koudstaal P.J. et al. Common carotid intima-media thickness and risk of stroke and myocardial infarction: the Rotterdam study // Circulation. - 1997. - Vol. 96. - P. 1432-1437.

60. Kitamura A., Iso H., Imano H., Ohira T. et al. Carotid intima-media thickness and plaque characteristics as a risk factor for stroke in Japanese elderly men // Stroke. - 2004. - Vol. 35. - P. 2788-2794.

61. Inaba Y., Chen J.A., Bergman S.R. Carotid plaque, compared with carotid intima-media thickness, more accurately predicts coronary artery disease events: A metaanalysis // Atherosclerosis. - 2011. - Vol. 220, № 1. - P. 128-133.

62. Elias-Smale S.E., Kavousi M., Verwoert G.C. et al. Common carotid intima-media thickness in cardiovascular risk s tratification of older people: the Rotterdam Study // Eur. J. Prev. Cardiol. - 2012. - Vol. 19, № 4. - P. 698-705.

63. Howard G., Sharrett A.R., Heiss G. et al. Carotid artery intimal-media thickness distribution in general populations as evaluated by B-mode ultrasound. ARIC Investigators // Stroke. - 1993. - Vol. 24. - P. 1297-1304.

64. Finn A.V., Kolodgie F.D., Virmani R. Correlation between carotid intimal/medial thickness and atherosclerosis: A point of view from pathology // Arterioscler. Thromb. Vasc. Biol. - 2010. - Vol. 30. - P. 177-181.

65. Jurcut C., Jurcut R. et al. Cardiovascular risk and rheumatoid arthritis: from mechanisms of atherosclerosis to therapeutic approach // Rom. J. Intern. Med. - 2004. - Vol. 42, № 4. - P. 659-669.

66. Bots M.L., Evans G.W., Riley W.A. et al. Carotid intima-media thickness measurements in intervention studies: design options, progression rates, and sample size considerations: a point of view // Stroke. - 2003. - Vol. 34. - P. 2985-2994.

67. The Edinburgh Artery Study American Heart Association, Inc. Coronary Heart Disease // Circulation. - 2004. - Vol. 110. - P. 3075-3080.

68. Newman A.B., Shemanski L., Manolio T.A. et al. Cardiovascular Health Study Group. Ankle-arm index as a predictor of cardiovascular disease and mortality in the Cardiovascular Health Study // Arterioscler. Thromb. Vasc. Biol. - 1999. - Vol. 19, № 3. - P. 538-545.

69. Weatherley B.D., Nelson J.J., Heiss G. et al. The association of the ankle-brachial index with incident coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) study, 1987-2001 // BMC Cardiovasc. Disord. - 2007. - Vol. 7, № 3. - [Электронный ресурс] doi:10.1186/1471-2261-7-3.

70. Resnick H.E., Lindsay R.S., McDermott M.M. et al. Relationship of high and low ankle brachial index to all-cause and cardiovascular disease mortality: the Strong Heart Study // Circulation. - 2004. - Vol. 109, № 6. - P. 733-739.

71. Fowkes F.G., Murray G.D. et al. Ankle Brachial Index Combined With Framingham Risk Score to Predict Cardiovascular Events and Mortality A Meta-analysis // JAMA. - 2008. - Vol. 300, № 2. - P. 197-208.

72. Murphy T.P., Dhangana R., Pencina M.J. et al. Ankle-brachial index and cardiovascular risk prediction: an analysis of 11,594 individuals with 10-year follow-up // Atherosclerosis. - 2008. - Vol. 220, № 1. - P. 160-167.

73. Takaki A., Ogawa H., Wakeyama T. et al. Cardio-Ankle Vascular Index Is Superior to Brachial-Ankle Pulse Wave Velocity as an Index of Arterial Stiffness // Hypertens. Res. - 2008. - Vol. 31, № 7. - P. 1347-1355.

74. Huck C.J., Bronas U.G., Williamson E.B. Noninvasive measurements of arterial stiffness: Repeatability and interrelationships with endothelial function and arterial morphology measures // Vascular Health and Risk Management. - 2007. - Vol. 3, № 3. - P. 343-349.

75. Izuhara M., Shioji K., Kadota S. et al. Relationship of Cardio-Ankle Vascular Index (CAVI) to Carotid and Coronary Arteriosclerosis // Circ. J. - 2008. - Vol. 72, № 1. - P. 1762-1767.

76. Yeboah J., McClelland R.L., Polonsky T.S. et al. Comparison of Novel Risk Markers for Improvement in Cardiovascular Risk Assessment in Intermediate-Risk Individuals // JAMA. - 2012. - Vol. 308, № 8. - P. 788-795.

77. Izuhara M., Shioji K., Kadota S. et al. Relationship of Cardio-Ankle Vascular Index (CAVI) to Carotid and Coronary Arteriosclerosis // Circ. J. - 2008. - Vol. 72, № 1. - P. 1762-1767.

78. Yeboah J., Folsom A.R., Burke G.L. Predictive value of brachial flow-mediated dilation for incident cardiovascular events in a population-based study: the multi-ethnic study of atherosclerosis // Circulation. - 2009. - Vol. 120, № 6. - P. 502-509.

79. Wald N.J., Law M.R. A strategy to reduce cardiovascular disease by more than 80 % // BMJ. - 2003. - Vol. 326. - P. 1419.

80. Yusuf S., Pais P., Afzal R. et al. Effects of a polypill (Polycap) on risk factors in middle-aged individuals without cardiovascular disease (TIPS): a phase II, doubleblind, randomised trial // Lancet. - 2009. - Vol. 373. - P. 1341-1351.

81. Cannon C.P. Can the polypill save the world from heart disease? // Lancet. - 2009. - Vol. 373. - P. 1313-1314.


Для цитирования:


Алиева А.С., Ротарь О.П., Конради А.О. Оценка субклинического поражения сосудов на популяционном уровне. Трансляционная медицина. 2014;(2):26-38. https://doi.org/10.18705/2311-4495-2014-0-2-26-38

For citation:


Alieva A.S., Rotar O.P., Konradi A.O. SUBCLINICAL VASCULAR DAMAGE ASSESSMENT ON POPULATION LEVEL. Translational Medicine. 2014;(2):26-38. (In Russ.) https://doi.org/10.18705/2311-4495-2014-0-2-26-38

Просмотров: 76


Creative Commons License
Контент доступен под лицензией Creative Commons Attribution 4.0 License.


ISSN 2311-4495 (Print)
ISSN 2410-5155 (Online)