Early repolarization on ECG (early repolarization pattern and syndrome)
https://doi.org/10.18705/2311-4495-2018-5-4-23-34
Abstract
Purpose To study the early repolarization pattern (ERP) in patient with nonischemic cardiomyopathies (acute myocarditis and arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C)).
Materials and methods: We analyzed 2 groups of patients: The 1st group — 29 patients with acute myocarditis (21 male, age 48,7±13,5); the 2nd — 51 patients with confirmed diagnose of ARVD/C (27 male, age 33±7). We used the criteria by Macfarlane P.W. et al., 2015 to identify ERP. Also we analyzed the results of endomiocardial biopsy (EMB).
Results: In the 1st group ERP was detected in 13,8% (4) patients), in the 2nd ERP was detected in 17,6% (9) patients. There was no significant difference between frequency of ERP in these groups (p>0.05In the 1st group in all patients was detected inflammation by EMB, myocardial fibrosis was found in 25% (1) patients. In the 2nd group in 22,2% (2) patients with ERP there were no structural abnormalities detected by EMB, and other 78% patients had residual myocytes.
Conclusions. On the example of myocarditis and ARVD/C we demonstrated that the ERP was not studied for all diseases that have a pathogenetic basis for its occurrence. Further prospective studies are necessary to evaluate the relationship with the arrhythmias, including malignant ones.
About the Authors
M. S. Gordeeva
Almazov National Medical Research Centre
Russian Federation
Competing Interests:
Russian Federation
Maria S. Gordeeva - postgraduate student.
Akkuratova str. 2, Saint Petersburg, 197341
Competing Interests:
No conflict of interest
I. A. Zemskov
Almazov National Medical Research Centre
Russian Federation
Competing Interests:
Russian Federation
Ivan A. Zemskov - postgraduate student.
Akkuratova str. 2, Saint Petersburg, 197341
Competing Interests:
No conflict of interest
A. A. Sokolova
Almazov National Medical Research Centre
Russian Federation
Competing Interests:
Russian Federation
Alena S. Sokolova - student, I.P. Pavlov First Saint Petersburg State Medical Unuversity.
Akkuratova str. 2, Saint Petersburg, 197341
Competing Interests:
No conflict of interest
E. V. Parmon
Almazov National Medical Research Centre
Russian Federation
Competing Interests:
Russian Federation
Elena V. Parmon - MD, assistant professor.
Akkuratova str. 2, Saint Petersburg, 197341
Competing Interests:
No conflict of interest
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Review
For citations:
Gordeeva M.S., Zemskov I.A., Sokolova A.A., Parmon E.V. Early repolarization on ECG (early repolarization pattern and syndrome). Translational Medicine. 2018;5(4):23-34. (In Russ.) https://doi.org/10.18705/2311-4495-2018-5-4-23-34
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