T2 * MAGNETIC-RESONANCE RELAXOMETRY IN NON-INVASIVE QUANTITATIVE IRON OVERLOAD ASSESSMENT OF LIVER AND HEART
https://doi.org/10.18705/2311-4495-2017-4-5-37-45
Abstract
For the purpose of an objective assessment of liver and heart iron overload in patients with hemochromatoses of various genesis, 60 patients underwent magnetic resonance imaging (MRI) using the T2 *-relaxometry technique.
The study was performed on a high-fi eld magnetic resonance scanner by induction of a magnetic fi eld of 1.5 T. A comparison was made of the data obtained during the MRI with the laboratory data of patients, namely, the concentration of serum ferritin.
As a result of the work it was shown that the technique T2 * MR -relaxometry is effective, to date provides the most accurate information from non-invasive methods for examining iron overload, and requires inclusion in the protocol of patients with suspicion of iron overload, especially when planning therapy with iron chelators.
About the Authors
A. M. Titova
Almazov National Medical Research Centre
Russian Federation
Russian Federation
PhD student, radiologist, National Almazov North-West Medical Research Centre
Akkuratova str. 2, Saint Petersburg, Russia, 197341
G. E. Trufanov
Almazov National Medical Research Centre
Russian Federation
MD, Dr Sci., Prof., National Almazov North-West Medical Research Centre ;
Russian Federation
MD, Dr Sci., Prof., National Almazov North-West Medical Research Centre ;
V. A. Fokin
Almazov National Medical Research Centre
Russian Federation
MD, Dr Sci., Prof., National Almazov North-West Medical Research Centre
Russian Federation
MD, Dr Sci., Prof., National Almazov North-West Medical Research Centre
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Review
For citations:
Titova A.M., Trufanov G.E., Fokin V.A. T2 * MAGNETIC-RESONANCE RELAXOMETRY IN NON-INVASIVE QUANTITATIVE IRON OVERLOAD ASSESSMENT OF LIVER AND HEART. Translational Medicine. 2017;4(5):37-45. (In Russ.) https://doi.org/10.18705/2311-4495-2017-4-5-37-45
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