TRANSLATIONAL RESEARCH AS A MODEL OF PROGRESS IN CURRENT MEDICAL SCIENCE
https://doi.org/10.18705/2311-4495-2014-0-1-13-22
Abstract
Translational medicine is a new concept which aims reduction of the distance between basic science discoveries and routine medical practice. This review focuses on the history of the concept of translational research in medicine and summarizes the current state of translational biomedical studies in USA and Europe. In addition, the phases and models of translational process are described, as well as the major translational barriers. Special attention is paid to the estimation of translation potential of new technologies which guarantees the success of translation. The problem of improved translation of new knowledge to clinical realm requires complex approach, including three basic principles: highest possible quality of research, perfect management of translational projects, and setting up an efficient dialogue between the representatives of different professional teams.
Keywords
трансляционная медицина,
трансляционные исследования,
трансляционные барьеры,
доклинические исследования,
разработка лекарственных препаратов,
лечебные и диагностические технологии,
биомедицинские инновации,
translational medicine,
translational research,
translational barriers,
preclinical studies,
drug development,
therapeutic and diagnostic techniques,
biomedical innovation
About the Author
Eugene V. Shlyakhto
Federal Almazov Medical Research Centre; First Pavlov State Medical University of St. Petersburg
Russian Federation
Russian Federation
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For citations:
Shlyakhto E.V. TRANSLATIONAL RESEARCH AS A MODEL OF PROGRESS IN CURRENT MEDICAL SCIENCE. Translational Medicine. 2014;(1):5-18. (In Russ.) https://doi.org/10.18705/2311-4495-2014-0-1-13-22
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