CONGENITAL CYSTIC ADENOMATOID MALFORMATION AND PULMONARY SEQUESTRATION IN INFANTS AND YOUNG CHILDREN
https://doi.org/10.18705/2311-4495-2016-3-6-40-45
Abstract
Background. Congenital cystic adenomatoid malformation (CCAM) and pulmonary sequestration (PS) occupy significant place in the structure of congenital malformations of lung. These defects subject to surgical correction in many cases. Diagnostic algorithm, age and volume of operation are discussed. General terms of the development of these malformations, occurring picture of combination of histological changes corresponding PS and CCAM, suggest a single origin of these defects. The propensity to infection and the development of inflammatory complications and malignancy define a common approach to the surgical treatment of these conditions.
Objective. Improve the results of treatment of children with CCAM and PS and analyze the experience for the period of 6 years in Federal Almazov North-West Medical Research Centre. Design and methods. 61 patients with CCAM and PS were treated. Patients underwent surgery with good and excellent immediate and long-term results.
Conclusions. Delivery in pregnant women with suspected or established diagnosis of lung malformation should be performed in a specialized perinatal centers with surgical and intensive care unit for newborns and experience in treating these patients. In the postnatal period necessary to carry out X-ray and CT scan with contrast, these types of surveys should also be used in all cases available according to the prenatal ultrasound of the suspected malformation of the lung. The optimal time for surgery — the first month of life.
About the Authors
S. V. Alexandrov
Federal Almazov North-West Medical Research Centre, Saint Petersburg; ST. MARY MAGDALENE CHILDREN’S CITY HOSPITAL № 2, Saint Petersburg
Russian Federation
Russian Federation
Sergey V. Alexandrov - deputy head doctor.
Akkuratova str. 2, Saint Petersburg, 197341, e-mail: dgb2spb@mail.ru
V. G. Bairov
Federal Almazov North-West Medical Research Centre
Russian Federation
Russian Federation
Vladimir G. Bairov - MD professor, head of the laboratory of surgery of congenital and hereditary pathology.
Saint Petersburg
N. A. Shchegoleva
Federal Almazov North-West Medical Research Centre
Russian Federation
Russian Federation
Natalia A. Shchegoleva - head of the Department of pediatric surgery malformations and acquired diseases (2010–2016).
Saint Petersburg
A. V. Yakovlev
Federal Almazov North-West Medical Research Centre
Russian Federation
Russian Federation
Alexander V. Yakovlev - head of Department of anesthesiology and intensive care in perinatal centre.
Saint Petersburg
References
1. Sfakianaki AK, Copel JA. Congenital Cystic Lesions of the Lung: Congenital Cystic Adenomatoid Malformation and Bronchopulmonary Sequestration. Rev Obstet Gynecol. 2012; 5(2): 85–93.
2. Laberge JM, Flageole H, Pugash D, et al. Outcome of the prenatally diagnosed congenital cystic adenomatoid lung malformation: a Canadian experience. Fetal Diagn Ther. 2001; 16(3): 178-186.
3. Gornall AS, Budd JL, Draper ES, et al. Congenital cystic adenomatoid malformation: accuracy of prenatal diagnosis, prevalence and outcome in a general population. Prenat Diagn. 2003; 23(12): 997-1002.
4. Ch’in K, Tang M. Congenital adenomatoid malformation of one lobe of a lung with general anasarca. Arch Pathol (Chic). 1949; 48(3): 221-229.
5. Conran RM, Stocker JT. Extralobar sequestration with frequently associated congenital cystic adenomatoid malformation, type 2: report of 50 cases. Pediatr Dev Pathol. 1999; 2(5): 454-463.
6. Davenport M, Warne SA, Cacciaguerra S, Patel S, Greenough A, Nicolaides K. Current outcome of antenally diagnosed cystic lung disease. J Pediatr Surg. 2004; 39(4): 549-556
7. Langston C. New concepts in the pathology of congenital lung malformations. Semin Pediatr Surg. 2003; 12(1): 17-37.
8. Laje P., Liechty K.W. Postnatal management and outcome of prenatally diagnosed lung lesions. Prenat Diagn. 2008; 28(7): 612-8.
9. Papagiannopoulos K, Hughes S, Nicholson AG, et al. Cystic lung lesions in the pediatric and adult population: surgical experience at the Brompton Hospital. Ann Thorac Surg. 2002; 73(5): 1594-1598.
10. Van Raemdonck D, De Boeck K, Devlieger H, et al. Pulmonary sequestration: a comparison between pediatric and adult patients. Eur J Cardiothorac Surg. 2001; 19(4): 388-395.
11. Nishibayashi SW, Andrassy RJ, Woolley MM. Congenital cystic adenomatoid malformation: 1 30-year experience. J Pediatr Surg. 1981; 16(5): 704-706.
12. Adzick NS, Harrison MR, Glick PL, et al., Fetal cystic adenomatoid malformation: prenatal diagnosis and natural history. J Pediatr Surg. 1985; 20(5): 483-488.
13. Stocker JT, Madewell JE, Drake RM. Congenital cystic adenomatoid malformation of the lung. Classification and morphologic spectrum. Hum Pathol. 1977; 8(2): 155-171.
14. Chow PC, Lee SL, Tang MHY, et al. Management and outcome of antenatally diagnosed congenital cystic adenomatoid malformation of the lung. Hong Kong Med J. 2007; 13: 31-39
15. Ko SF, Ng SH, Lee TY, Wan YL, Liang CD, Lin JW, Chen WJ, Hsieh MJ. Noninvasive imaging of bronchopulmonary sequestration.AJR Am J Roentgenol. 2000; 175(4): 1005-1012.
16. Berrocal T, Madrid C, Novo S, et al. Congenital anomalies of the tracheobronchial tree, lung, and mediastinum: embryology, radiology, and pathology. Radiographics. 2004; 24(1): e17.
17. d’Agostino S, Bonoldi E, Dante S, et al. Embryonal rhabdomyosarcoma of the lung arising in cystic adenomatoid malformation: case report and review of the literature. J Pediatr Surg. 1997; 32(9): 1381-1383.
18. Kaslovsky RA, Purdy S, Dangman BC, et al. Bronchioloalveolar Carcinoma in a Child With Congenital Cystic Adenomatoid Malformation. Chest. 1997; 112(2): 548-551.
19. Shanti CM, Klein MD. Cystic lung disease. Semin Pediatr Surg. 2008; 17(1): 2-8.
Review
For citations:
Alexandrov S.V., Bairov V.G., Shchegoleva N.A., Yakovlev A.V. CONGENITAL CYSTIC ADENOMATOID MALFORMATION AND PULMONARY SEQUESTRATION IN INFANTS AND YOUNG CHILDREN. Translational Medicine. 2016;3(6):40-45. (In Russ.) https://doi.org/10.18705/2311-4495-2016-3-6-40-45
Views:
1477
Email this article 