A case of fetal intrauterine tachycardia with further catamnestic observation of a child with WPW syndrome for 10 years
https://doi.org/10.18705/2311-4495-2025-12-2-153-160
EDN: EWBBRN
Abstract
The article describes a clinical case of a child with a common cardiac problem — Wolff-Parkinson-White syndrome (WPW), which often debuts with attacks of achycardie paroxystique AV-receveuse (PAVRT) already in utero and recurs in the postnatal period. It is a well-known fact that fetal tachyarrhythmias can cause not only non-immune hydrops as a symptom of heart failure, but also cause antenatal fetal death. The anatomical and physiological basis of Wolff-Parkinson-White syndrome are additional atrioventricular connections, which can conduct impulses from the atria to the ventricles, causing their pre-excitation. We present a clinical observation of a child with an intermittent type of WPW syndrome. The attacks manifested in utero. However, after the early neonatal period, paroxysms of tachycardia did not bother the patient for a long time. At an older age, the method of choice is RFA, after which attacks of PAVRT most often do not recur. This clinical case demonstrates the need for dynamic observation of patients with fetal tachycardia detected in utero, since attacks can recur at any age. The role of parents in recognizing the clinical manifestations of an attack of paroxysmal tachycardia for timely termination of the paroxysm is also important.
About the Authors
D. I. SadykovaRussian Federation
Dinara I. Sadykova - MD, Professor, Head of the Department of Hospital Pediatrics of Kazan State Medical University.
Kazan, Republic of Tatarstan
Competing Interests:
None
D. R. Sabirova
Russian Federation
Dina R. Sabirova - PhD, Associate Professor of the Department of Hospital Pediatrics of Kazan State Medical University.
Kazan, Republic of Tatarstan
Competing Interests:
None
I. G. Yunusova
Russian Federation
Ilsiyar G. Yunusova - Student of Pediatrics at Kazan State Medical University.
Butlerova str., 49, Kazan, Republic of Tatarstan, 420012
Competing Interests:
None
A. V. Ugadyarova
Russian Federation
Angelina V. Ugadyarova - Student of Pediatrics at Kazan State Medical University.
Kazan, Republic of Tatarstan
Competing Interests:
None
References
1. Yuan SM, Xu ZY. Fetal arrhythmias: prenatal assessment and intrauterine therapy. Ital J Pediatr. 2020;46:21. https://doi.org/10.1186/s13052-020-0785-9
2. Alsaied T, Baskar S, Fares M, et al. First-Line Antiarrhythmic Transplacental Treatment for Fetal Tachyarrhythmia: A Systematic Review and Meta-Analysis. J Am Heart Assoc. 2017 Dec 15;6(12): e007164. DOI:10.1161/JAHA.117.007164. PMID: 29246961; PMCID: PMC5779032.
3. Ardashev AV, Rybachenko MS, Zhelyakov EG, et al. Wolff-Parkinson-White syndrome: classification, clinical manifestations, diagnosis and treatment. Cardiology. 2009;10:84–94. In Russian.
4. Moak JR Supraventricular tachycardia in the neonate and infant. Prog PediatrCardiol. 2000;11(1):25–38. DOI:10.1016/s1058-9813(00)00033-3.
5. Kovalev IA, Khamnagadayev IA, Svintsova LI, et al. Supraventricular tachycardia in children. Pediatric Pharmacology. 2019;16(3):133–143. In Russian. DOI:10.15690/pf.v16i3.2024.
6. Zasim EV, Strogii VV. WPW syndrome in childhood: unsolved problems. Emergency cardiology and cardiovascular risks. 2019;3(1):462–473. In Russian. http://rep.bsmu.by:8080/handle/BSMU/24940
7. Anjewierden S, Humpherys J, LaPage MJ, et al. Detection of Tachyarrhythmias in a Large Cohort of Infants Using Direct-to-Consumer Heart Rate Monitoring. J Pediatr. 2021 May;232:147–153.e1. DOI:10.1016/j.jpeds.2020.12.080. Epub 2021 Jan 6. PMID: 33421423.
8. Diagnostics and treatment of cardiac rhythm and conduction disorders in children: a tutorial / edited by M. A. Shkolnikova, D. F. Egorov. SPb: Chelovek, 2012. P. 432. In Russian. ISBN 978-5-93339-177-7.
9. Peregudina OL, Vasichkina ES, Chueva KA, et al. Efficiency of radiofrequency ablation in children and adolescents with tachyarrhythmias: a two-year study experience. Pediatric Heart and Vascular Diseases. 2023;3(20):110–117. In Russian. DOI:10.24022/1810-0686-2023-20-2-110-117.
10. Tatarsky BA. Supraventricular tachycardias // Cardiology. National Guidelines / edited by E. V. Shlyakhto. 2nd ed., revised and enlarged. Moscow: GEOTAR-Media, 2021. In Russian. ISBN 978-5-9704-6092-4.
11. Bokeria EL. Fetal tachyarrhythmias: current state of the problem. Doctor.Ru. 2021;20(8):64–69. In Russian. DOI: 10.31550/1727-2378-2021-20-8-64-69.
12. Ministry of Health of the Russian Federation. Bupivacaine: instructions for medical use of the medicinal product. LP-N(004171)-(RG-RU). In Russian.
13. Riveros-Perez E, Polania-Gutierrez JJ, Avella-Molano B. Fetal heart rate changes and labor neuraxial analgesia: a machine learning approach. BMC PregnancyChildbirth. 2023;23:329. https://doi.org/10.1186/s12884-023-05632-3
14. Clinical guidelines “Singleton birth, delivery by cesarean section” Russian Society of Obstetricians and Gynecologists, LLC “Association of Anesthesiologists and Resuscitators (AAR)”, Association of Obstetric Anesthesiologists and Resuscitators. 2021. In Russian. https://cr.minzdrav.gov.ru/schema/639_1
15. Kruchina TK. Wolff-Parkinson-White syndrome in children: clinical features, diagnostics, treatment / T. K. Kruchina, E. S. Vasichkina, G. A. Novik. Pediatric pharmacology. 2011;8(5):49–53. In Russian.
16. Brugada J, Blom N, Sarquella-Brugada G, et al. Pharmacological and non-pharmacological therapy for arrhythmias in the pediatric population: EHRA and AEPC-Arrhythmia Working Group joint consensus statement. Europace. 2013;15:1337–1382.
17. Kruchina TK, Novik GA, Egorov DF. Vagal maneuvers for stopping tachycardia attacks in children: evaluation of clinical and electrophysiological factors of the Valsalva maneuver effectiveness. Pediatric Pharmacology. 2015;12(6):639–644. In Russian. DOI:10.15690/pf.v12i6.1486.
18. Ministry of Health of the Russian Federation. Sodium adenosine triphosphate: instructions for medical use of the drug. LP-004667. In Russian.
Review
For citations:
Sadykova D.I., Sabirova D.R., Yunusova I.G., Ugadyarova A.V. A case of fetal intrauterine tachycardia with further catamnestic observation of a child with WPW syndrome for 10 years. Translational Medicine. 2025;12(2):153-160. (In Russ.) https://doi.org/10.18705/2311-4495-2025-12-2-153-160. EDN: EWBBRN