RADIONUCLIDE ASSESSMENT OF RIGHT VENTRICLE CONTRACTILE DYSFUNCTION IN PATIENTS WITH MITRAL VALVE STENOSIS
https://doi.org/10.18705/2311-4495-2014-0-4-19-24
Abstract
Purpose. To assess the value of gated blood pool SPECT in assessment of right ventricle (RV) contractility in patients with rheumatic mitral stenosis (MS). Materials and methods. The study included 20 patients (mean age 54,2 ± 8,22 years) with rheumatic MS, 13 patients were examined before and after correction of mitral defect. All patients underwent gated blood pool SPECT before and after mitral valve replacement. Results. All patients with mitral stenosis show fixed RV regional wall contractility reduction. Patients with MS, in comparison with control group patients show significantly lower values of EF, the MSI and the MFR/3, SV, and larger values of RV EDV. Mitral valve replacement realized in statistically significant decrease of ESV, increasing of MSI and RV EF. The size of the right atrium, measured by blood pool SPECT, was significantly increased in patients with MS, and significantly decreased after mitral valve replacement. Conclusion. Gated blood pool SPECT can be used for noninvasive assessment of functional status of the right ventricle in patients with rheumatic mitral stenosis.
About the Authors
K. V. Zavadovsky
Research Institute for Cardiology; National Research Tomsk Polytechnic University
Russian Federation
Russian Federation
A. V. Evtushenko
Research Institute for Cardiology
Russian Federation
Russian Federation
V. V. Saushkin
Research Institute for Cardiology
Russian Federation
Russian Federation
Yu. B. Lishmanov
Research Institute for Cardiology; National Research Tomsk Polytechnic University
Russian Federation
Russian Federation
References
1. Бураковский В.И. и др. Сердечно-сосудистая хирургия: руководство / В.И. Бураковский, Л.А. Бокерия и др.; Под ред. акад. АМН СССР В.И. Бураковского, проф. Л.А. Бокерия. - М.: Медицина, 1989. -752 с.
2. de Groote P., Millaire A., Foucher-Hossien C. et al. Right ventricular ejection fraction is an independent predictor of survival in patients with moderate heart failure. - J. Am. Coll. Cardiol. - 1998. - Vol. 32. - P. 948-954.
3. Haddad F., Hunt S.A., Rosenthal D.N. et al. Right ventricular function in cardiovascular disease, part I: Anatomy, physiology, aging, and functional assessment of the right ventricle. - Circulation. - 2008. - Vol. 117, № 11. - P. 1436-1448.
4. Tugcu A., Yildirimtürk O., Tayyareci Y. et al. Evaluation of subclinical right ventricular dysfunction in obstructive sleep apnea patients using velocity vector imag ing. - Circ. J. - 2010. - Vol. 74, № 2. - P. 312-319.
5. Miller S., Reissen R., Claussen C. et al. Cardiac Imaging. - Stuttgart - New York: Thieme, 2007.
6. Alfakih K., Plein S., Thiele H. et al. Normal human left and right ventricular dimensions for MRI as assessed by turbo gradient echo and steady-state free precession imaging sequences. - J. Magn. Reson. Imaging. - 2003. - Vol. 17. - P. 323-329.
7. Daou D., Van Kriekinge S.D., Coaguila C. et al. Automatic quantification of right ventricular function with gated blood pool SPECT. - J. Nucl. Cardiol. - 2004. - Vol. 11, № 3. - P. 242-244.
8. Fauchier L., Marie O., Casset-Senon D. et al. Interventricular and intraventricular dyssynchrony in idiopathic dilated cardiomyopathy: a prognostic study with Fourier phase analysis of radionuclide angioscintigraphy. - J. Am. Col.l Cardiol. - 2002. - Vol. 40, № 11. - P. 2022-2030.
9. Ghio S., Constantin. C., Klersy C. et al. Interventricular and intraventricular dyssynchrony are common in heart failure patients, regardless of QRS duration. - Eur. Heart J. - 2004. - Vol. 25, № 7. - P. 571-578.
10. Schwartz D.J., Kop W.J., Park M.H. et al. Evidence for early right ventricular and septal mechanical activation (interventricular dyssynchrony) in pulmonary hypertension. - Am. J. Cardiol. - 2008.-Vol. 102, № 9. - P. 1273-1277.
11. Chen J., Boogers M.M., Bax J.J. et al. The use of nuclear imaging for cardiac resynchronization therapy. - Curr. Cardiol. Rep. - 2010. - Vol. 12, № 2. - P. 185191.
12. Raymond R.J., Hinderliter A.L., Willis P.W. et al. Echocardiographic predictors of adverse outcomes in primary pulmonary hypertension. - J. Am. Coll. Cardiol. - 2002. - Vol. 39, № 7. - P. 1214-1219.
13. Cioffi G., de Simone G., Mureddu G. et al. C. Right atrial size and function in patients with pulmonary hypertension associated with disorders of respiratory system or hypoxemia. - Eur. J. Echocardiogr. - 2007. - Oct. - Vol. 8, № 5. - P. 322-331.
Review
For citations:
Zavadovsky K.V., Evtushenko A.V., Saushkin V.V., Lishmanov Yu.B. RADIONUCLIDE ASSESSMENT OF RIGHT VENTRICLE CONTRACTILE DYSFUNCTION IN PATIENTS WITH MITRAL VALVE STENOSIS. Translational Medicine. 2014;(4):19-24. (In Russ.) https://doi.org/10.18705/2311-4495-2014-0-4-19-24
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