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EPIDEMIOLOGY, CLINICAL AND MORPHOLOGICAL FEATURES OF INFECTIVE Q-FEVER ENDOCARDITIS

https://doi.org/10.18705/2311-4495-2014-0-3-39-43

Abstract

Culture-negative endocarditis remains a diagnostic and therapeutic challenge despite recent medical advances. Coxiella burnetii, the causative pathogen of Q-fever, weight with etiological structure of infective endocarditis. However, laboratory diagnosis is often underinformative, because the growth of C. burnetii in hemoculture is difficult and serological response can be paradoxical. The difficulties of diagnostic at Q-fever endocarditis motivate the consideration of the epidemiological characteristics and pathogenesis of Q-fever. These insights should help redefine preventive and therapeutic strategies against infective endocarditis.

About the Authors

O. A. Freylikhman
St. Petersburg Pasteur Institute; Federal Almazov Medical Reseach Centre
Russian Federation


N. K. Tokarevich
St. Petersburg Pasteur Institute
Russian Federation


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Review

For citations:


Freylikhman O.A., Tokarevich N.K. EPIDEMIOLOGY, CLINICAL AND MORPHOLOGICAL FEATURES OF INFECTIVE Q-FEVER ENDOCARDITIS. Translational Medicine. 2014;(3):39-43. (In Russ.) https://doi.org/10.18705/2311-4495-2014-0-3-39-43

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ISSN 2311-4495 (Print)
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