Left atrial appendage occluder implantation for prevention of systemic embolism. First experience in the north-west region
https://doi.org/10.18705/2311-4495-2016-3-3-59-66
Abstract
The first experience of various LAA occluders implantation in the North-West region for prevention of systemic thromboembolic events is reported. The implantation procedure is considered to be rather safety and effective and provides an opportunity for subsequent oral anticoagulants withdrawal. Therefore LAA occluder implantation can be an alternative in patients with high risk of bleeding and contraindications for permanent anticoagulation.
About the Authors
Andrey M. Osadchy
City Hospital № 40
Russian Federation
Russian Federation
Maxim V. Agarkov
City Hospital № 40
Russian Federation
Russian Federation
Sergey V. Vlasenko
City Hospital № 40
Russian Federation
Russian Federation
Oksana F. Stovpyuk
Federal Almazov Medical Research Centre
Russian Federation
Russian Federation
Natalia E. Pavlova
City Hospital № 40
Russian Federation
Russian Federation
Olga P. Mamaeva
City Hospital № 40
Russian Federation
Russian Federation
Julia V. Miller
Federal Almazov Medical Research Centre
Russian Federation
Russian Federation
Alexander V. Kamenev
Federal Almazov Medical Research Centre
Russian Federation
Russian Federation
Sergey V. Gureev
Federal Almazov Medical Researh Centre
Russian Federation
Russian Federation
Dmitriy S. Lebedeva
Federal Almazov North-West Medical Research Centre
Russian Federation
Russian Federation
Sergey G. Shcherbak
Head of City Hospital № 40
Russian Federation
Russian Federation
Dmitriy S. Lebedev
Federal Almazov North-West Medical Research Centre
Russian Federation
Russian Federation
References
1. Go A.S., et al. Heart Disease and Stroke Statistics-2014 Update. Circulation. 2014; 128: 00-00
2. Watson T., Shantsila E., Lip G.Y. Mechanisms of thrombogenesis in atrial fibrillation: Virchow’s triad revisited. Lancet. 2009; 373: 155-166.
3. Zateyschikov D.A., Zotova I.V., Dankovtseva E.N. et al. Thrombotic events and antithrombotic therapy for arrhythmias. M.: Practice, 2011. p. 264. In Russian [Затейщиков Д.А., Зотова И.В., Данковцева Е.Н., Сидоренко Б.А. Тромбозы и антитромботическая терапия при аритмиях. М.: Практика, 2011. c. 264]
4. Marini C., De Santis F., Sacco S., et al. Contribution of atrial fibrillation to incidence and outcome of ischemic stroke: results from a population-based study. Stroke. 2005; 36: 1115-1119.
5. Lip G.Y., Nieuwlaat R., Pisters R. et al. Refining clinical risk stratification for predicting stroke and thromboembolism in atrial fibrillation using a novel risk factor based approach: the euro heart survey on atrial fibrillation. Chest. 2010; 137(2): 263-272.
6. Lip G.Y., Frison L., Halperin J.L. et all. Comparative validation of a novel risk score for predicting bleeding risk in anticoagulated patients with atrial fibrillation: the HAS-BLED score. J Am CollCardiol. 2011; 173-180.
7. Lip GY, Edwards SJ. Stroke prevention with aspirin, warfarin and ximelagatran in patients with nonvalvular atrial fibrillation: a systematic review and metaanalysis. ThrombRes. 2006;118: 321-333.
8. Hart R.G., Pearce L.A., Aguilar M.I. Meta-analysis: antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation.Ann Intern Med. 2007; 146(12): 857-867.
9. Connolly S.J., Ezekowitz M.D., Yusuf S., et al. Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med. 2009; 361(12): 1139-1151.
10. Patel M.R., Mahaffey K.W., Gard J., et al. Rivaroxaban versus warfarin in nonvalvular atrial fibrillation. N Engl J Med. 2011; 365(10): 883-891.
11. Granger C.B., Alexander J.H., McMurray J.J. et al. Apixaban versus warfarin in patients with atrial fibrillation. N Engl J Med. 2011; 365(11): 981-992.
12. Stroke Prevention in Atrial Fibrillation Study. Final results. Circulation. 1991; 84(2): 527-539.
13. Reddy V.Y., Holmes D., Doshi S.K., et al. Safety of percutaneous left atrial appendage closure: results from the Watchman Left Atrial Appendage System for Embolic Protection in Patients with AF (PROTECT AF) clinical trial and the Continued Access Registry. Circulation. 2011; 123: 417-424.
14. Reddy V.Y., Doshi S.K., Sievert H., et al. PROTECT AF Investigators. Percutaneous left atrial appendage closure for stroke prophylaxis in patients with atrial fibrillation: 2.3-year follow-up of the PROTECT AF (Watchman Left Atrial Appendage System for Embolic Protection in Patients with Atrial Fibrillation) Trial. Circulation. 2013; 127(6): 720-729.
15. Holmes D.R.Jr., Kar S., Price M.J., et al. Prospective randomized evaluation of the Watchman Left Atrial Appendage Closure device in patients with atrial fibrillation versus long-term warfarin therapy: the PREVAIL trial. J AmCollCardiol. 2014; 64(1): 1-12.
16. Meier B., Blaauw Y., Khattab A.A. et all. EHRA/ EAPCI expert consensus statement on catheter-based left atrial appendage occlusion. EuroIntervention. 2014; 10: 1109-1125.
17. Boersma L., Schmidt B., Betts T. et all. EWOLUTION: design of a registry to evaluate real-world clinical outcomes in patients with AF and high stroke risk-treated with the WATCHMAN left atrial appendage closure technology. Catheter Cardiovasc Interv. 2016; in press.
18. Holmes D.R. Jr., Kar S., Price M.J. et all. Prospective randomized evaluation of the WATCHMAN left atrial appendage closure device in patients with atrial fibrillation versus long-term warfarin therapy: the PREVAIL trial. J AmCollCardiol. 2014; 64: 1-12.
19. Tzikas A., Shakir S., Gafoor S., Omran H., Berti S., Santoro G., Kefer J., Landmesser U., Nielsen-Kudsk J.E., Cruz-Gonzalez I., Sievert H., Tichelbäcker T., Kanagaratnam P., Nietlispach F., Aminian A., Kasch F., Freixa X., Danna P., Rezzaghi M., Vermeersch P., Stock F., Stolcova M., Costa M., Ibrahim R., Schillinger W., Meier B., Park J.W. Left atrial appendage occlusion for stroke prevention in atrial fibrillation: multicentre experience with the AMPLATZER Cardiac Plug. EuroIntervention. 2016; 11(10): 1170-1179.
20. Mikhaylov E.N., Lebedev D.S., Gureev S.V. et al. Safety of combination of indirect and direct anticoagulants during catheter ablation of atrial fibrillation: a study on a large group of patients. Journal of arrhythmology. 2008; 53: 21-26. In Russian [Михайлов Е.Н., Лебедев Д.С., Гуреев С.В. и др. Безопасность одновременного применения непрямых и прямых антикоагулянтов при катетерной аблации фибрилляции предсердий: исследование на большой группе пациентов. Вестник аритмологии. 2008; 53: 21-26.]
Review
For citations:
Osadchy A.M., Agarkov M.V., Vlasenko S.V., Stovpyuk O.F., Pavlova N.E., Mamaeva O.P., Miller J.V., Kamenev A.V., Gureev S.V., Lebedeva D.S., Shcherbak S.G., Lebedev D.S. Left atrial appendage occluder implantation for prevention of systemic embolism. First experience in the north-west region. Translational Medicine. 2016;3(3):59-66. (In Russ.) https://doi.org/10.18705/2311-4495-2016-3-3-59-66
Views:
622
Email this article 