Ventricular lead position and the response to cardiac resynchronization therapy
https://doi.org/10.18705/2311-4495-2016-3-3-49-58
Abstract
A retrospective study involving 40 patients, based on the initial division of the patients into 2 groups: group I (N = 20) - high response to cardiac resynchronization therapy (CRT) and group II (N = 20) - lack of response to CRT. Criteria of CRT efficacy were: decrease in end-systolic left ventricular volume equal to or more than 15 %, relative increase in left ventricular ejection fraction equal to or greater than 10 %, decrease in functional class of chronic heart failure (NYHA) equal to 1 or greater. Low response of CRT was determined as the absence of criteria said above (the lack of positive dynamics in left ventricle diameters and volumes, ejection fraction, or it had a negative value in the form of further enlargement of the heart chambers and the reduction of its contractile capacity). The initial patient separation by the degree of response to cardiac resynchronization therapy suggests verification the hypothesis that a different response to CRT may be associated with the relative position of the ventricle electrodes and the parameters of ventricular myocardial dyssynchrony.
About the Authors
Tamara A. Lubimceva
Federal Almazov NorthWest Medical Research Centre
Russian Federation
Russian Federation
Viktoriya K. Lebedeva
Federal Almazov North-West Medical Research Centre
Russian Federation
Russian Federation
Mariya A. Trukshina
Federal Almazov North-West Medical Research Centre
Russian Federation
Russian Federation
Elena A. Lyasnikova
Federal Almazov North-West Medical Research Centre
Russian Federation
Russian Federation
Dmitriy S. Lebedev
Federal Almazov North-West Medical Research Centre
Russian Federation
Russian Federation
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Review
For citations:
Lubimceva T.A., Lebedeva V.K., Trukshina M.A., Lyasnikova E.A., Lebedev D.S. Ventricular lead position and the response to cardiac resynchronization therapy. Translational Medicine. 2016;3(3):49-58. (In Russ.) https://doi.org/10.18705/2311-4495-2016-3-3-49-58
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