<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">transmed</journal-id><journal-title-group><journal-title xml:lang="ru">Трансляционная медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Translational Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2311-4495</issn><issn pub-type="epub">2410-5155</issn><publisher><publisher-name>Almazov National Medical Research Centre, Saint Petersburg, Russia</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18705/2311-4495-2024-11-3-294-303</article-id><article-id custom-type="elpub" pub-id-type="custom">transmed-920</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АКУШЕРСТВО И ГИНЕКОЛОГИЯ</subject></subj-group></article-categories><title-group><article-title>Основные адаптационные механизмы женского организма, обеспечивающие внутриутробное развитие плода</article-title><trans-title-group xml:lang="en"><trans-title>The main adaptive mechanisms of the female body that ensure the intrauterine development of the fetus</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Маркина</surname><given-names>А. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Markina</surname><given-names>A. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Маркина Алина Евгеньевна, ассистент кафедры акушерства и гинекологии имени профессора А. П. Марусова</p><p>ул. Большевистская, д. 68, Саранск, Республика Мордовия, 430005</p></bio><bio xml:lang="en"><p>Alina E. Markina, Assistant at the Department of Obstetrics and Gynecology named after Professor A. P. Marusov</p><p>Bolshevistskaya str., 68, Saransk, Republic of Mordovia, 430005</p></bio><email xlink:type="simple">university11.05.1976@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лабзина</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Labzina</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лабзина Маргарита Владимировна, к.м.н., доцент кафедры акушерства и гинекологии</p><p>Саранск</p></bio><bio xml:lang="en"><p>Margarita V. Labzina, PhD, Associate Professor of the Department of Obstetrics and Gynecology</p><p>Saransk</p></bio><email xlink:type="simple">university11.05.1976@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Романова</surname><given-names>Э. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Romanova</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Романова Элла Викторовна, к.х.н., доцент кафедры биологической и фармацевтической химии с курсом организации и управления фармацией</p><p>Саранск</p></bio><bio xml:lang="en"><p>Ella V. Romanova, PhD, Associate Professor of the Department of Biological and Pharmaceutical Chemistry with a course in organization and Management of Pharmacy</p><p>Saransk</p></bio><email xlink:type="simple">university11.05.1976@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Емельский</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Yemelskiy</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Емельский Никита Андреевич, врач-терапевт</p><p>Электросталь</p></bio><bio xml:lang="en"><p>Nikita A. Yemelskiy, general practitioner</p><p>Saransk</p></bio><email xlink:type="simple">university11.05.1976@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение высшего образования «Национальный исследовательский Мордовский государственный университет имени Н. П. Огарёва»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Ogarev National Research Mordovian State University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Общество с ограниченной ответственностью «Эльма»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Elma LLC</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>04</day><month>08</month><year>2024</year></pub-date><volume>11</volume><issue>3</issue><fpage>294</fpage><lpage>303</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Маркина А.Е., Лабзина М.В., Романова Э.В., Емельский Н.А., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Маркина А.Е., Лабзина М.В., Романова Э.В., Емельский Н.А.</copyright-holder><copyright-holder xml:lang="en">Markina A.E., Labzina M.V., Romanova E.V., Yemelskiy N.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://transmed.almazovcentre.ru/jour/article/view/920">https://transmed.almazovcentre.ru/jour/article/view/920</self-uri><abstract><p>Адаптационные механизмы, рассмотренные авторами исследования, играют решающую роль в подготовке организма женщины к предстоящей беременности. Особенно важным аспектом исследования является изучение характера адаптационного синдрома после успешного оплодотворения яйцеклетки и оценка эффективности адаптивных реакций. Отмечается, что согласованность и последовательность адаптационных механизмов организма женщины на различных этапах полового акта имеют критическое значение для успешного оплодотворения яйцеклетки. Исследование подчеркивает важность правильного функционирования этих механизмов в контексте беременности и рождения здорового потомства. Понимание этих аспектов позволяет более глубоко взглянуть на процессы, происходящие в организме женщины во время зачатия и влияющие на дальнейшее развитие плода. Всестороннее изучение адаптационных процессов при оплодотворении способствует повышению эффективности репродуктивной системы и обеспечивает благоприятные условия для начала новой жизни. Авторами подчеркивается, что адаптационные механизмы играют важную роль в подготовке организма женщины.</p></abstract><trans-abstract xml:lang="en"><p>The adaptation mechanisms considered by the authors of the study play a decisive role in preparing a woman’s body for the upcoming pregnancy. A particularly important aspect of the study is to study the nature of the adaptation syndrome after successful fertilization of the egg and assess the effectiveness of adaptive reactions. It is noted that the consistency and consistency of the adaptation mechanisms of the woman’s body at various stages of sexual intercourse are critical for the successful fertilization of the egg. The study highlights the importance of proper functioning of these mechanisms in the context of pregnancy and the birth of healthy offspring. Understanding these aspects allows us to take a deeper look at the processes occurring in a woman’s body during conception and inﬂuencing the further development of the fetus. A comprehensive study of adaptation processes during fertilization helps to increase the efﬁciency of the reproductive system and provides favorable conditions for starting a new life. The authors emphasize that adaptation mechanisms play an important role in preparing a woman’s body.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>адаптационный механизм</kwd><kwd>беременность</kwd><kwd>имплантация</kwd><kwd>оплодотворение</kwd><kwd>трофобласт</kwd><kwd>эмбрион</kwd></kwd-group><kwd-group xml:lang="en"><kwd>adaptation mechanism</kwd><kwd>embryo</kwd><kwd>fertilization</kwd><kwd>implantation</kwd><kwd>pregnancy</kwd><kwd>trophoblast</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Лабзина М.В., Тултаева Е.Д., Савочкина А.С. Адаптационные механизмы подготовки женского организма к беременности. Тенденции развития науки и образования. 2023. № 98–8. С. 90–92. DOI 10.18411/trnio-06-2023-423. EDN IXJBSV.</mixed-citation><mixed-citation xml:lang="en">Labzina MV, Tultayeva ED, Savochkina AS. Adaptive mechanisms of preparation of the female body for pregnancy. Trends in the development of science and education. 2023. No. 98–8. P. 90–92. In Russian DOI 10.18411/trnio-06-2023-423. EDN IXJBSV.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Gaiton AK. Medical physiology / A. K. Gaiton, J. E. Hall / Translated from English; Edited by V. I. Kobrin. M.: Logosphere, 2008. In Russian. ISBN 978-5-98657-013-6.</mixed-citation><mixed-citation xml:lang="en">Gaiton AK. Medical physiology / A. K. Gaiton, J. E. Hall / Translated from English; Edited by V. I. Kobrin. M.: Logosphere, 2008. In Russian ISBN 978-5-98657-013-6.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Секреторная фаза эндометриального цикла. Механизм менструации // МедУнивер URL: https://meduniver.com/Medical/Physiology/1367.html (дата обращения: 01.09.2023).</mixed-citation><mixed-citation xml:lang="en">The secretory phase of the endometrial cycle. The mechanism of menstruation // MedUniver URL: https://meduniver.com/Medical/Physiology/1367.html (date of application: 09/01/2023).</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Peck JR, Waxman D. What Is Adaptation and How Should It Be Measured? J Theor Biol. 2018 Jun 14;447:190– 198. DOI: 10.1016/j.jtbi.2018.03.003.</mixed-citation><mixed-citation xml:lang="en">Peck JR, Waxman D. What Is Adaptation and How Should It Be Measured? J Theor Biol. 2018 Jun 14;447:190– 198. DOI: 10.1016/j.jtbi.2018.03.003.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Robker RL, Hennebold JD, Russell DL. Coordination of Ovulation and Oocyte Maturation: A Good Egg at the Right Time. Endocrinology. 2018 Sep;159 (9): 3209–3218. DOI: 10.1210/en.2018-00485.</mixed-citation><mixed-citation xml:lang="en">Robker RL, Hennebold JD, Russell DL. Coordination of Ovulation and Oocyte Maturation: A Good Egg at the Right Time. Endocrinology. 2018 Sep;159 (9): 3209–3218. DOI: 10.1210/en.2018-00485.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">El-Hayek S, Clarke HJ. Control of Oocyte Growth and Development by Intercellular Communication Within the Follicular Niche. Results Probl Cell Differ. 2016;58: 191–224. DOI: 10.1007/978-3-319-31973-5_8.</mixed-citation><mixed-citation xml:lang="en">El-Hayek S, Clarke HJ. Control of Oocyte Growth and Development by Intercellular Communication Within the Follicular Niche. Results Probl Cell Differ. 2016;58: 191–224. DOI: 10.1007/978-3-319-31973-5_8.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Jarrell J. The Signiﬁcance and Evolution of Menstruation. Best Pract Res Clin Obstet Gynaecol. Jul 2018; 50: 18–26. DOI: 10.1016/j.bpobgyn.2018.01.007.</mixed-citation><mixed-citation xml:lang="en">Jarrell J. The Signiﬁcance and Evolution of Menstruation. Best Pract Res Clin Obstet Gynaecol. Jul 2018; 50: 18–26. DOI: 10.1016/j.bpobgyn.2018.01.007.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Kay T, Lehmann L, Keller L. Kin selection and altruism. Curr Biol. 2019 Jun 3; 29 (11): R438–R442. DOI: 10.1016/j.cub.2019.01.067.</mixed-citation><mixed-citation xml:lang="en">Kay T, Lehmann L, Keller L. Kin selection and altruism. Curr Biol. 2019 Jun 3; 29 (11): R438–R442. DOI: 10.1016/j.cub.2019.01.067.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Leiva R, Bouchard T, Boehringer H, et al. Random serum progesterone threshold to conﬁrm ovulation. Steroids. 2015 Sep; 101:125–9. DOI: 10.1016/j.steroids.2015.06.013.</mixed-citation><mixed-citation xml:lang="en">Leiva R, Bouchard T, Boehringer H, et al. Random serum progesterone threshold to conﬁrm ovulation. Steroids. 2015 Sep; 101:125–9. DOI: 10.1016/j.steroids.2015.06.013.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Bin Guo. Regulatory Mechanism of Embryo Implantation. Sheng Li Xue Bao. 2020 Feb 25; 72 (1): 105–114.</mixed-citation><mixed-citation xml:lang="en">Bin Guo. Regulatory Mechanism of Embryo Implantation. Sheng Li Xue Bao. 2020 Feb 25; 72 (1): 105– 114.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Maliqueo M, Echiburú B, Crisosto N. Sex Steroids Modulate Uterine-Placental Vasculature: Implications for Obstetrics and Neonatal Outcomes. Front Physiol. 2016;7:152. DOI: 10.3389/fphys.2016.00152.</mixed-citation><mixed-citation xml:lang="en">Maliqueo M, Echiburú B, Crisosto N. Sex Steroids Modulate Uterine-Placental Vasculature: Implications for Obstetrics and Neonatal Outcomes. Front Physiol. 2016;7:152. DOI: 10.3389/fphys.2016.00152.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Ashary N, Tiwari A, Modi D. Embryo Implantation: War in Times of Love. Endocrinology. 2018 Feb 1;159 (2): 1188–1198. DOI: 10.1210/en.2017-03082.</mixed-citation><mixed-citation xml:lang="en">Ashary N, Tiwari A, Modi D. Embryo Implantation: War in Times of Love. Endocrinology. 2018 Feb 1;159 (2): 1188–1198. DOI: 10.1210/en.2017-03082.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Staud F, Karahoda R. Trophoblast: The central unit of fetal growth, protection and programming. IntJBiochemCellBiol. Dec 2018;105: 35–40. DOI: DOI: 10.1016/j.biocel.2018.09.016.</mixed-citation><mixed-citation xml:lang="en">Staud F, Karahoda R. Trophoblast: The central unit of fetal growth, protection and programming. IntJBiochemCellBiol. Dec 2018;105: 35–40. DOI: DOI: 10.1016/j.biocel.2018.09.016.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Odland Karlsen H, Johnsen SL, Rasmussen S, et al. The human yolk sac size reﬂects involvement in embryonic and fetal growth regulation. Acta Obstet Gynecol Scand. Feb 2019;98 (2): 176–182. DOI: 10.1111/aogs.13466.</mixed-citation><mixed-citation xml:lang="en">Odland Karlsen H, Johnsen SL, Rasmussen S, et al. The human yolk sac size reﬂects involvement in embryonic and fetal growth regulation. Acta Obstet Gynecol Scand. Feb 2019;98 (2): 176–182. DOI: 10.1111/aogs.13466.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Assessment of groundwater quality and their vulnerability to pollution using GQI and DRASTIC indices / S. Mardiana, R. Anzum, N. K. A. Dwijendra, et al. // Journal of Water and Land Development. 2022. Vol. 53. P. 138–142. DOI 10.24425/jwld.2022.140789. EDN VAWQHE.</mixed-citation><mixed-citation xml:lang="en">Assessment of groundwater quality and their vulnerability to pollution using GQI and DRASTIC indices / S. Mardiana, R. Anzum, N. K. A. Dwijendra, et al. // Journal of Water and Land Development. 2022. Vol. 53. P. 138–142. DOI 10.24425/jwld.2022.140789. EDN VAWQHE.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Route Optimization of Container Ships Using Differential Evolution and Gray Wolf Optimization / J. Dalle, P. Chetthamrongchai, G. Widjaja, et al. // Industrial Engineering and Management Systems. 2021. Vol. 20, No. 4. P. 604–612. DOI 10.7232/iems.2021.20.4.604. EDN HXQIJU.</mixed-citation><mixed-citation xml:lang="en">Route Optimization of Container Ships Using Differential Evolution and Gray Wolf Optimization / J. Dalle, P. Chetthamrongchai, G. Widjaja, et al. // Industrial Engineering and Management Systems. 2021. Vol. 20, No. 4. P. 604–612. DOI 10.7232/iems.2021.20.4.604. EDN HXQIJU.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
