transmedТрансляционная медицинаTranslational Medicine2311-44952410-5155Almazov National Medical Research Centre, Saint Petersburg, Russia10.18705/311-4495-2024-11-3-253-263transmed-909Research ArticleОБЗОРЫПотенциал интеграции последовательности ДВИ в комплексные МРТ исследования. Литературный обзорThe potential of integrating motion sequences into comprehensive MRT studies. Literature reviewЛевандовскийЕ. В.LevandouskiYe. V.

Левандовский Евгений Валерьевич, к.м.н., врач-рентгенолог кабинета рентгеновской компьютерной диагностики отделения лучевой диагностики

ул. Орловская, д. 66, Минск, 220053

Yevgeni V. Levandouski, PhD, Radiologist, Radiological dept.

Orlovskaya str., 66, Minsk, 220053

Lewandowski10mg@gmail.comУлезкоЕ. А.UlezkaE. A.

Улезко Елена Альбертовна, д.м.н., профессор, заместитель директора по педиатрии

Минск

Elena A. Ulezka, MD, Professor, Assistant director of pediatrics

Minsk

ulezko@tut.byГольцевМ. В.GoltsevM. V.

Гольцев Михаил Всеволодович, к.ф.-м.н., доцент, заведующий кафедрой медицинской и биологической физики

Минск

Mikhail V. Goltsev, PhD, Associate Professor, Head of Dept of Medical and Biological Physics

Minsk

mgoltsev@mail.ruГосударственное учреждение «Республиканский научно-практический центр «Мать и дитя»БеларусьRepublican scientific and practical center “Mother and child”BelarusУчреждение образования «Белорусский государственный медицинский университет»БеларусьBelarusian state medical universityBelarus202404082024113253263Copyright © Левандовский Е.В., Улезко Е.А., Гольцев М.В., 20242024Левандовский Е.В., Улезко Е.А., Гольцев М.В.Levandouski Y.V., Ulezka E.A., Goltsev M.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://transmed.almazovcentre.ru/jour/article/view/909

В клинической практике активно применяется метод диффузионно-взвешенной МРТ, с помощью которой можно получить диффузионно-взвешенные изображения (ДВИ), представляющие собой методы визуализации броуновского движения молекул воды в биологических тканях. Согласно общеизвестным оценкам, организм человека примерно на 60–85 % состоит из воды, а в цитоплазме клетки, являющейся структурной и функциональной единицей живой биоткани, содержится 75–85 % воды, которая является растворителем для органических и неорганических веществ и участвует в метаболизме и терморегуляции. Диффузионно-взвешенные изображения позволяют качественно и количественно оценить информацию об особенностях движения протонов водорода в зоне интереса. Целью данного литературного обзора стояло более углубленное изучение не только спектра клинического применения последовательности ДВИ, но также ее физических основ для оптимизации протоколов сканирования путем корректирования настроек аппаратуры для получения более информативных результатов.

The diffusion-weighted MRI method has been actively used in clinical practice to obtain diffusion-weighted images (DWI), which are methods of visualizing the Brownian motion of water molecules in biological tissues. According to well-known estimates, the human body consists of about 60–85 % water, and the cytoplasm of the cell, which is a structural and functional unit of living tissues, contains 75–85 % water, which is a solvent for organic and inorganic substances, and is involved in metabolism and thermoregulation. Diffusion-weighted imaging allows qualitative and quantitative assessment of information about hydrogen proton motion patterns in the zone of interest. The aim of this literature review was to further explore not only the spectrum of clinical applications of DWI sequence, but also its physical basis for the possibility of optimizing scanning protocols by adjusting instrument settings to obtain more informative results.

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The authors declare that there are no conflicts of interest present.