transmedТрансляционная медицинаTranslational Medicine2311-44952410-5155Almazov National Medical Research Centre, Saint Petersburg, Russia10.18705/2311-4495-2024-11-2-191-200OFCIMQtransmed-882Research ArticleЭНДОКРИНОЛОГИЧЕСКИЕ ЗАБОЛЕВАНИЯMETABOLIC DISEASESСтрессорная гипергликемия у пациентов без сахарного диабетаStress hyperglycemia in non-diabetic patientsМануйловаЮ. А.ManuylovaYu. A.

Мануйлова Юлия Александровна - к.м.н., заведующий отделением эндокринологии, старший научный сотрудник отдела внутренних болезней МНОЦ МГУ.

пр. Ломоносовский, д. 27, корп. 10, Москва, 119192

Yulia A. Manuylova - PhD, Head of the Department of Endocrinology, Senior Researcher at the Department of Internal Diseases of the Medical Research and Educational Center of Moscow State University.

Lomonosovsky ave., 27, building 10, Moscow, 119192

juliakolish@yahoo.comПавликоваЕ. П.PavlicovaE. P.

Павликова Елена Петровна - д.м.н., профессор, заместитель главного врача по лечебной работе, заведующий отделом внутренних болезней МНОЦ МГУ.

Москва

Elena P. Pavlicova - MD, Professor, Deputy Chief Physician for Medical Work, Head of the Department of Internal Diseases, Medical Research and Educational Center of Moscow State University.

Moscow

ПотапенкоА. В.PotapenkoA. V.

Потапенко Антон Валерьевич - к.м.н., заведующий клинико-диагностическим отделением МНОЦ МГУ.

Москва

Anton V. Potapenko - PhD, Head of the Clinical and diagnostic Department, Medical Research and Educational Center of Moscow State University.

Moscow

ТрухановаМ. A.TruhanovaM. A.

Труханова Мария Александровна - к.м.н., врач-реаниматолог МНОЦ МГУ.

Москва

Mariya A. Truhanova - Candidate of Medical Sciences, resuscitator, Medical Research and Educational Center of Moscow State University.

Moscow

КлементьеваА. Г.KlementyevaA. G.

Клементьева Анна Григорьевна - заведующий приемным отделением МНОЦ МГУ.

Москва

Anna G. Klementyeva - Head of the Reception Department, Medical Research and Educational Center of Moscow State University.

Moscow

Федеральное государственное бюджетное образовательное учреждение высшего образования «Московский государственный университет имени М.В. Ломоносова», Медицинский научно-образовательный центрРоссияMedical Research and Educational Center of Moscow State UniversityRussian Federation202420062024112191200Copyright © Мануйлова Ю.А., Павликова Е.П., Потапенко А.В., Труханова М.A., Клементьева А.Г., 20242024Мануйлова Ю.А., Павликова Е.П., Потапенко А.В., Труханова М.A., Клементьева А.Г.Manuylova Y.A., Pavlicova E.P., Potapenko A.V., Truhanova M.A., Klementyeva A.G.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://transmed.almazovcentre.ru/jour/article/view/882

Стрессорная гипергликемия — физиологический защитный механизм, проявляющийся в повышении гликемии при остром неблагополучии. Несмотря на то, что наличие этого феномена и его неблагоприятное воздействие на организм не подвергаются сомнению, до сих пор нет алгоритмов периоперационного ведения пациентов без сахарного диабета в анамнезе: обязательного контроля гликемии, частоты контроля, точки вмешательства для глюкозы, оптимального режима инсулинотерапии, методов нивелирования повышения уровня глюкозы. В данном обзоре обсуждаются дефиниции стрессорной гипергликемии, патогенез, влияние ее на организм человека, cut-off для глюкозы, предикторы гипергликемии и возможные способы предотвращения неблагоприятных последствий.

Поиск литературных источников проводился в системах Pubmed, E-library, Cochrane library с 1995 по 2023 гг.

Stress hyperglycemia is a physiological defense mechanism that manifests itself in an increase in glycemia in acute distress. Despite the fact that the presence of this phenomenon and its adverse effects on the body are not in doubt, there are still no algorithms for intraoperative management of patients without a history of diabetes mellitus: mandatory control of glycemia, frequency of control, intervention points for glucose, optimal insulin therapy regimen, methods for leveling glucose levels. This review discusses the definitions of stress hypoglycemia, pathogenesis, its effect on the human body, cut-off for glucose, predictors of hyperglycemia and possible ways to prevent adverse effects.

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The authors declare that there are no conflicts of interest present.