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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">transmed</journal-id><journal-title-group><journal-title xml:lang="ru">Трансляционная медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Translational Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2311-4495</issn><issn pub-type="epub">2410-5155</issn><publisher><publisher-name>Almazov National Medical Research Centre, Saint Petersburg, Russia</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18705/2311-4495-2023-10-6-581-590</article-id><article-id custom-type="edn" pub-id-type="custom">PLFQUI</article-id><article-id custom-type="elpub" pub-id-type="custom">transmed-839</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НЕВРОЛОГИЯ И НЕЙРОХИРУРГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>NEUROLOGY AND NEUROSURGERY</subject></subj-group></article-categories><title-group><article-title>Верхнешейная симпатэктомия при нейроваскулярной патологии.</article-title><trans-title-group xml:lang="en"><trans-title>Upper cervical sympathectomy in neurovascular pathology.</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Веснина</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Vesnina</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Веснина Анастасия Андреевна, младший научный сотрудник научно-исследовательской лаборатории патологии мозгового кровообращения</p><p>ул. Маяковского, д. 12, Санкт-Петербург, 191014</p></bio><bio xml:lang="en"><p>Anastasiia A. Vesnina, Junior researcher of the Research Laboratory of Cerebral Circulation Pathology</p><p>Mayakovskaya str., 12, Saint Petersburg, 191014</p></bio><email xlink:type="simple">anastasya.vesnina@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Самочерных</surname><given-names>К. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Samochernykh</surname><given-names>K. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Самочерных Константин Александрович, д.м.н., профессор РАН, директор</p></bio><bio xml:lang="en"><p>Konstantin A. Samochernykh, Doctor of Medical Sciences, Professor of the Russian Academy of Science, Director</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Семенютин</surname><given-names>В. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Semenyutin</surname><given-names>V. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Семенютин Владимир Борисович, д.б.н., профессор, заведующий научно-исследовательской лабораторией патологии мозгового кровообращения</p></bio><bio xml:lang="en"><p>Vladimir B. Semenyutin, Doctor of Biological Sciences, Professor, Head of the Research Laboratory of Cerebral Circulation Pathology</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Российский научно-исследовательский нейрохирургический институт имени профессора А. Л. Поленова — филиал Федерального государственного бюджетного учреждения «Национальный медицинский исследовательский центр имени В. А. Алмазова» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Polenov Russian Scientific Research Institute of Neurosurgery— branch of the Almazov National Medical Research Centre</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>20</day><month>12</month><year>2023</year></pub-date><volume>10</volume><issue>6</issue><fpage>581</fpage><lpage>590</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Веснина А.А., Самочерных К.А., Семенютин В.Б., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Веснина А.А., Самочерных К.А., Семенютин В.Б.</copyright-holder><copyright-holder xml:lang="en">Vesnina A.A., Samochernykh K.A., Semenyutin V.B.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://transmed.almazovcentre.ru/jour/article/view/839">https://transmed.almazovcentre.ru/jour/article/view/839</self-uri><abstract><p>Эффективность верхнешейной симпатэктомии при лечении пациентов с нейроваскулярной патологией обсуждается в работах исследователей в течение многих лет. Однако показания к проведению данной операции до сих пор нуждаются в уточнении. Динамика мозгового кровотока при проведении симпатической блокады не смогла стать однозначным критерием определения показаний к оперативному лечению. Изменение церебрального перфузионного давления при нейроваскулярной патологии может активировать нейрогенный механизм регуляции мозгового кровотока. Обоснована необходимость поиска новых методов оценки интенсивности воздействия вегетативной нервной системы на тонус мозговых сосудов (нейрогенного механизма регуляции мозгового кровотока) для уточнения показаний к проведению верхнешейной симпатэктомии у больных с нейроваскулярной патологией. В обзоре высказывается гипотеза о связи внутричерепных В-волн с состоянием нейрогенного механизма регуляции мозгового кровотока.</p></abstract><trans-abstract xml:lang="en"><p>The effectiveness of upper cervical sympathectomy in the treatment of patients with neurovascular pathology has been discussed in the researcher’s article for many years. However, the indications for this surgery need still to be clarified. The dynamics of cerebral blood flow during sympathetic blockade could not become the significant criterion for determining indications for surgical treatment. A cerebral perfusion pressure change in neurovascular pathology can activate the neurogenic mechanism of cerebral blood flow regulation. The need to search for new methods for the intensity of the autonomic nervous system impact on the cerebral vessels tone (the neurogenic mechanism of cerebral blood flow regulation) to clarify the indications for upper cervical sympathectomy in patients with neurovascular pathology is justified. The review put forward a hypothesis about the relationship between intracranial B-waves amplitude and the state of the neurogenic mechanism of cerebral blood flow regulation.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>блокада симпатического ганглия</kwd><kwd>верхнешейная симпатэктомия</kwd><kwd>внутричерепные В-волны</kwd><kwd>нейрогенный механизм</kwd><kwd>регуляция мозгового кровотока</kwd><kwd>церебральное перфузионное давление</kwd></kwd-group><kwd-group xml:lang="en"><kwd>cerebral blood flow regulation</kwd><kwd>cerebral perfusion pressure</kwd><kwd>intracranial B-waves</kwd><kwd>neurogenic mechanism</kwd><kwd>sympathetic ganglion blockade</kwd><kwd>upper cervical sympathectomy</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Средства государственного задания Минздрава России № 056-00017-23-00 (на 2023 г. и на плановый период 2024 и 2025 гг.); тема: «Разработка малоинвазивной системы непрерывной оценки биомеханических свойств краниоспинальной системы ликворообращения и корковой перфузии»; ЕГИСУ НИОКТР: 121031100314-1.</funding-statement><funding-statement xml:lang="en">Funds of the state task of the Ministry of Health of the Russian Federation No. 056-00017-23-00 (for 2023 and for the planning period 2024 and 2025); topic: «Development of a minimally invasive system for continuous assessment of the biomechanical properties of the craniospinal fluid circulation system and cortical perfusion»; EGISU R&amp;D: 121031100314-1.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">GBD 2015 Disease and Injury Incidence and Prevalence Collaborators. 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