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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">transmed</journal-id><journal-title-group><journal-title xml:lang="ru">Трансляционная медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Translational Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2311-4495</issn><issn pub-type="epub">2410-5155</issn><publisher><publisher-name>Almazov National Medical Research Centre, Saint Petersburg, Russia</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18705/2311-4495-2022-9-2-27-36</article-id><article-id custom-type="elpub" pub-id-type="custom">transmed-683</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СЕРДЕЧНО-СОСУДИСТЫЕ ЗАБОЛЕВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CARDIOVASCULAR MEDICINE</subject></subj-group></article-categories><title-group><article-title>Возможности длительного мониторирования электрокардиограммы у пациентов с инфарктом миокарда: чем дольше, тем лучше?</article-title><trans-title-group xml:lang="en"><trans-title>Capabilities of long-term ECG monitoring in patients with myocardial infarction: the longer, the better?</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7463-9259</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Олейников</surname><given-names>В. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Oleynikov</surname><given-names>V. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Олейников Валентин Эливич - доктор медицинских наук,  профессор, заведующий кафедрой «Терапия»</p><p>ул. Красная, 40, Пенза, 440026</p></bio><bio xml:lang="en"><p>Valentin E. Oleynikov, DM, Prof., Head of the Department of Therapy</p><p>Krasnaya str., 40, Penza, 440026</p></bio><email xlink:type="simple">v.oleynikof@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9925-2096</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аверьянова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Averyanova</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Аверьянова Елена Владимировна - к.м.н., доцент кафедры «Терапия»</p><p>Пенза</p></bio><bio xml:lang="en"><p>Elena V. Averyanova, Ph.D. of Medical Sciences, Associate Professor at the Department of Therapy</p><p>Penza</p></bio><email xlink:type="simple">averyanova-elena90@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5647-9837</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Орешкина</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Oreshkina</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Орешкина Анастасия Александровна - врач-кардиолог, аспирант кафедры "Терапия" по направлению "Кардиология"</p><p>Пенза</p></bio><bio xml:lang="en"><p>Anastasia A. Oreshkina, Роstgraduate student at the Department of Therapy</p><p>Penza</p></bio><email xlink:type="simple">anast.oreschckina@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5111-6247</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Барменкова</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Barmenkova</surname><given-names>Yu. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Барменкова Юлия Андреевна, к.м.н., ассистент кафедры «Терапия»</p><p>Пенза</p></bio><bio xml:lang="en"><p>Yulia A. Barmenkova, Ph.D. of Medical Sciences</p><p>Penza</p></bio><email xlink:type="simple">yulenka.gsk@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2988-5530</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кулюцин</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kulyutsin</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кулюцин Алексей Валерьевич, зав. отделением кардиологии №5 с палатой реанимации и интенсивной терапии, к.м.н., доцент кафедры «Терапия», ФГБОУ ВО «Пензенский государственный университет»</p><p>Пенза</p></bio><bio xml:lang="en"><p>Aleksey V. Kulyutsin, Ph.D. of Medical Sciences, Associate Professor at the Department of Therapy Medical Institute, Penza State University, Head Department of Cardiology No. 5 with a resuscitation and intensive care</p><p>Penza</p></bio><email xlink:type="simple">kulyutsin0903@mail.com</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение высшего образования «Пензенский государственный университет»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Penza State University, Medical Institute</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Государственное бюджетное учреждение здравоохранения «Пензенская областная клиническая больница имени Н. Н. Бурденко»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Penza Regional Clinical Hospital N. N. Burdenko</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>15</day><month>06</month><year>2022</year></pub-date><volume>9</volume><issue>2</issue><fpage>27</fpage><lpage>36</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Олейников В.Э., Аверьянова Е.В., Орешкина А.А., Барменкова Ю.А., Кулюцин А.В., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Олейников В.Э., Аверьянова Е.В., Орешкина А.А., Барменкова Ю.А., Кулюцин А.В.</copyright-holder><copyright-holder xml:lang="en">Oleynikov V.E., Averyanova E.V., Oreshkina A.A., Barmenkova Y.A., Kulyutsin A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://transmed.almazovcentre.ru/jour/article/view/683">https://transmed.almazovcentre.ru/jour/article/view/683</self-uri><abstract><sec><title>Актуальность</title><p>Актуальность. В современной кардиологии 24-часовое мониторирование электрокардиограммы (ЭКГ) имеет высокую диагностическую ценность, однако у данного метода есть ряд недостатков при выявлении эпизодов неустойчивых жизнеопасных нарушений ритма. Увеличение продолжительности мониторирования ЭКГ до 72–120 часов позволяет расширить возможности диагностики жизнеугрожающих аритмий и их предикторов.</p></sec><sec><title>Цель</title><p>Цель. Изучить возможности длительного мониторирования ЭКГ (48–120 часов) в выявлении жизнеугрожающих аритмических событий и параметров электрической нестабильности миокарда у больных, перенесших инфаркт миокарда с подъемом сегмента ST (ИМпST).</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. В исследование включен 71 пациент c ИМпST. Всем пациентам с 4-х суток ИМпST выполняли многосуточное мониторирование ЭКГ по 3-м отведениям с использованием комплекса телеметрической регистрации ЭКГ со средней продолжительностью регистрации 90,4 ± 30,2 часов. На основании полученных записей был проведен анализ эпизодов ишемии миокарда, нарушений ритма и проводимости, турбулентности и вариабельности сердечного ритма, поздних потенциалов желудочков и дисперсии интервала QT в течение 5 суток.</p></sec><sec><title>Результаты</title><p>Результаты. Длительное мониторирование ЭКГ по сравнению со стандартным 24-часовым продемонстрировало достоверное преимущество при обнаружении желудочковой экстрасистолии высоких градаций. Анализ эпизодов ишемии миокарда в постинфарктном периоде выявил значимые различия по данным мониторирования ЭКГ в течение 120 часов в сравнении с результатами ЭКГ за 24 часа. При оценке патологической ТСР многосуточное мониторирование ЭКГ позволило в 2 раза чаще выявлять дисфункцию вегетативной регуляции сердечной деятельности у больных.</p></sec><sec><title>Заключение</title><p>Заключение. Комплексная оценка возможностей многосуточного мониторирования ЭКГ является перспективным направлением в прогнозировании тяжелых нарушений ритма у пациентов в постинфарктном периоде.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Background</title><p>Background. In modern cardiology, 24-hour electrocardiogram (ECG) monitoring has a high diagnostic value, but this method has a number of disadvantages in detecting episodes of unstable life-threatening arrhythmias. An increase in ECG monitoring duration allows expanding the possibilities of diagnosing life-threatening arrhythmias.</p></sec><sec><title>Objective</title><p>Objective. To study the possibilities of long-term ECG monitoring (48–120 hours) in the detection of life-threatening arrhythmic events and parameters of myocardial electrical instability in patients with ST-segment elevation myocardial infarction (STEMI).</p></sec><sec><title>Design and methods</title><p>Design and methods. The study included 71 STEMI patients. All patients from the 4th day of STEMI underwent multi-day ECG monitoring in 3 leads using a telemetric ECG recording complex with an average recording duration of 90.4 ± 30.2 hours. The analysis of episodes of myocardial ischemia, rhythm and conduction disturbances, turbulence and heart rate variability, late ventricular potentials and dispersion of the QT interval within 5 days was carried out.</p></sec><sec><title>Results</title><p>Results. Long-term monitoring allowed detecting high-grade ventricular extrasystoles. Analysis of episodes of myocardial ischemia in the postinfarction period revealed significant differences in the data of 120h-ECG monitoring in comparison with 24h-ECG. Multiday ECG monitoring made it possible to detect dysfunction of the autonomic regulation of cardiac activity in patients 2 times more often.</p></sec><sec><title>Conclusion</title><p>Conclusion. A comprehensive assessment of the possibilities of multi-day ECG monitoring is a promising direction in predicting severe arrhythmias in patients in the postinfarction period.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>жизнеугрожающие нарушения ритма</kwd><kwd>инфаркт миокарда</kwd><kwd>многосуточное мониторирование ЭКГ</kwd><kwd>параметры электрической нестабильности миокарда</kwd></kwd-group><kwd-group xml:lang="en"><kwd>markers of myocardial electrical instability</kwd><kwd>multi-day ECG monitoring</kwd><kwd>myocardial infarction</kwd><kwd>severe arrhythmias</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Работа выполнена при финансовой помощи гранта Президента РФ для государственной поддержки молодых российских ученых — кандидатов наук. Название проекта: «Роль электрофизиологического и морфологического состояния миокарда в развитии сердечной недостаточности и аритмических событий в постинфарктном периоде» (МК-1954.2022.3).</funding-statement><funding-statement xml:lang="en">The work was carried out with the financial assistance of a grant from the President of the Russian Federation for state support of young Russian scientists — candidates of sciences. Project title: “The role of the electrophysiological and morphological state of the myocardium in the development of heart failure and arrhythmic events in the post-infarction period” (MK-1954.2022.3).</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Аверьянов А.В., Адрианов А.В., Ардашев А.В. и др. Внезапная сердечная смерть. / Под ред. Шляхто Е. В. и др. 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