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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">transmed</journal-id><journal-title-group><journal-title xml:lang="ru">Трансляционная медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Translational Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2311-4495</issn><issn pub-type="epub">2410-5155</issn><publisher><publisher-name>Almazov National Medical Research Centre, Saint Petersburg, Russia</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18705/2311-4495-2020-7-5-29-42</article-id><article-id custom-type="elpub" pub-id-type="custom">transmed-583</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НЕВРОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>NEUROLOGY</subject></subj-group></article-categories><title-group><article-title>Новые диагностические и прогностические биомаркеры ишемических поражений мозга</article-title><trans-title-group xml:lang="en"><trans-title>New diagnostic and prognostic biomarkers of the ischemic brain damage</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4441-1165</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алексеева</surname><given-names>Т. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Alekseeva</surname><given-names>T. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алексеева Татьяна Михайловна, д.м.н., доцент, заведующая кафедрой неврологии и психиатрии</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Alekseeva Tat’yana M., MD, PhD, Dr. Sci., Head of the Department of Neurology and Psychiatry</p><p>Saint Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0175-3085</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Топузова</surname><given-names>М. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Topuzova</surname><given-names>M. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Топузова Мария Петровна, к.м.н., доцент кафедры неврологии и психиатрии</p><p>SPIN-код: 1091-9433 WOS Research ID: S-8865-2017 Scopus Author ID: 57201374816 AuthorID (РИНЦ): 922244</p><p>ул. Аккуратова, д. 2, Санкт-Петербург, 197341</p></bio><bio xml:lang="en"><p>Topuzova Mariya P., MD, PhD, Associate Professor of the Department of Neurology and Psychiatry</p><p>Akkuratova str. 2, Saint Petersburg, 197341</p></bio><email xlink:type="simple">topuzova_mp@almazovcentre.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1140-8039</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чайковская</surname><given-names>А. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Chaykovskaya</surname><given-names>A. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Чайковская Александра Дмитриевна, аспирант кафедры неврологии и психиатрии</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Chaykovskaya Alexandra D., MD, Postgraduate Student of the Department of Neurology and Psychiatry</p><p>Saint Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3637-5405</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Панина</surname><given-names>Е. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Panina</surname><given-names>Elena B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Панина Елена Борисовна, к.м.н., доцент кафедры неврологии и психиатрии</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Panina Elena B., MD, PhD, Associate Professor of the Department of Neurology and Psychiatry</p><p>Saint Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8537-3639</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Вавилова</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Vavilova</surname><given-names>T. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Вавилова Татьяна Владимировна, д.м.н., профессор, заведующая кафедрой лабораторной медицины и генетики</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Vavilova Tat’yana V., MD, PhD, Dr. Sci., Professor, Head of the Department of Laboratory Medicine and Genetics</p><p>Saint Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3553-6537</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Поспелова</surname><given-names>М. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Pospelova</surname><given-names>M. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Поспелова Мария Львовна, д.м.н., ведущий научный сотрудник НИЛ неврологии и нейрореабилитации, доцент кафедры неврологии и психиатрии</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Pospelova Maria L., MD, PhD, Leading Researcher of Neurology and Neurorehabilitation Scientific Research Department</p><p>Saint Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2115-8873</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Васильева</surname><given-names>Е. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Vasilieva</surname><given-names>E. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Васильева Елена Юрьевна, заведующая Центральная клинико-диагностическая лаборатория, ассистент кафедры лабораторной медицины и генетики</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Vasilieva Elena Yu., MD, Head of Central Clinical Diagnostics Laboratory, Assistant of the Department of Laboratory Medicine and Genetics</p><p>Saint Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Симаков</surname><given-names>К. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Simakov</surname><given-names>K. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Симаков Каюм Владимирович, руководитель Регионального сосудистого центра, заведующий неврологическим отделением для лечения больных с острыми нарушениями мозгового кровообращения</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Simakov Kayum V., MD, Head of the Regional Vascular Center, Head of the Neurological Department forthe Treatment of Patients with Acute Disorders of Cerebral Circulation</p><p>Saint Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2949-6268</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сергеева</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sergeeva</surname><given-names>T. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сергеева Татьяна Васильевна, к.м.н., заместитель главного врача по неврологии (руководитель Регионального сосудистого центра)</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Sergeeva Tat’yana V., MD, PhD, Deputy Chief Physician for Neurology (Head of the Regional Vascular Center)</p><p>Saint Petersburg</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр имени B. A. Алмaзoвa» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Almazov National Medical Research Centre</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Санкт-Петербургское государственное бюджетное учреждение здравоохранения «Городская больница Cвятой преподобномученицы Елизаветы»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Holy Martyr Elizabeth City Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>12</day><month>10</month><year>2020</year></pub-date><volume>7</volume><issue>5</issue><fpage>29</fpage><lpage>42</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Алексеева Т.М., Топузова М.П., Чайковская А.Д., Панина Е.Б., Вавилова Т.В., Поспелова М.Л., Васильева Е.Ю., Симаков К.В., Сергеева Т.В., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Алексеева Т.М., Топузова М.П., Чайковская А.Д., Панина Е.Б., Вавилова Т.В., Поспелова М.Л., Васильева Е.Ю., Симаков К.В., Сергеева Т.В.</copyright-holder><copyright-holder xml:lang="en">Alekseeva T.M., Topuzova M.P., Chaykovskaya A.D., Panina E.B., Vavilova T.V., Pospelova M.L., Vasilieva E.Y., Simakov K.V., Sergeeva T.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://transmed.almazovcentre.ru/jour/article/view/583">https://transmed.almazovcentre.ru/jour/article/view/583</self-uri><abstract/><trans-abstract xml:lang="en"/><kwd-group xml:lang="ru"><kwd>биомаркеры инсульта</kwd><kwd>глиальный фибриллярный кислый белок</kwd><kwd>инсульт</kwd><kwd>ишемический инсульт</kwd><kwd>краткосрочный исход</kwd><kwd>нейрон-специфическая енолаза</kwd><kwd>прогноз NR2-антитела</kwd><kwd>N-метил-D-аспартат рецепторы</kwd></kwd-group><kwd-group xml:lang="en"><kwd>stroke</kwd><kwd>stroke biomarker</kwd><kwd>neuron-specific enolase</kwd><kwd>glial fibrillary acidic protein</kwd><kwd>NR2-antibodies</kwd><kwd>N-methyl-D-aspartate receptors</kwd><kwd>short-term outcome</kwd><kwd>prognosis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Feigin VL, Norrving B, George MG, et al. 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