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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">transmed</journal-id><journal-title-group><journal-title xml:lang="ru">Трансляционная медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Translational Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2311-4495</issn><issn pub-type="epub">2410-5155</issn><publisher><publisher-name>Almazov National Medical Research Centre, Saint Petersburg, Russia</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18705/2311-4495-2019-6-2-5-11</article-id><article-id custom-type="elpub" pub-id-type="custom">transmed-459</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НЕВРОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>NEUROLOGY</subject></subj-group></article-categories><title-group><article-title>Современный взгляд на проблему формирования суицидального поведения у пациентов с фармакорезистентной формой эпилепсии в послеоперационном периоде (литературный обзор)</article-title><trans-title-group xml:lang="en"><trans-title>The Modern View on the Problem of Formation of Suicidal Behavior in Patients with a Pharmacoresistance Form of Epilepsy in the Postoperative Period (Review).</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шова</surname><given-names>Н. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Shova</surname><given-names>N. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шова Наталья Игоревна - аспирант отделения реабилитации больных с психосоматическими расстройствами.</p><p>Ул. Бехтерева, д. 3, Санкт-Петербург, 196019</p></bio><bio xml:lang="en"><p>Natalya I. Shova - Postgraduate Student of the Department of Rehabilitation of Patients With Psychosomatic Disorders.</p><p>Bekhterev str. 3, Saint Petersburg, 196019</p></bio><email xlink:type="simple">skins_cassi@outlook.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Михайлов</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Mikhailov</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Михайлов Владимир Алексеевич - доктор медицинских наук, заместитель директора по инновационному научному развитию и международному сотрудничеству, руководитель международного отдела, главный научный сотрудник и научный руководитель отделения реабилитации больных с психосоматическими расстройствами.</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Mikhalov Vladimir A. - PhD, Dr. Sc., Deputy Director for Innovative Scientific Development and International Cooperation, Head of the International Department, Chief Researcher and Scientific Director of the Department of Rehabilitation of patients with psychosomatic disorders.</p><p>Saint Petersburg</p></bio><email xlink:type="simple">vladmikh@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7186-0054</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Одинцова</surname><given-names>Г. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Odintsova</surname><given-names>G. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Одинцова Галина Вячеславовна - кандидат медицинских наук, старший научный сотрудник.</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Odintsova Galina V. - PhD, Senior Researcher, Department of Epileptology.</p><p>Saint Petersburg</p></bio><email xlink:type="simple">ajo@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дружинин</surname><given-names>А. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Druzhinin</surname><given-names>A. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Дружинин Андрей Константинович - кандидат медицинских наук, младший научный сотрудник отделения реабилитации больных с психосоматическими расстройствами.</p></bio><bio xml:lang="en"><p>Druzhinin Andrey K. - PhD, Junior Research of the Department of Rehabilitation of Patients With Psychosomatic Disorders.</p><p>Saint Petersburg</p></bio><email xlink:type="simple">ankod63@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Попов</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Popov</surname><given-names>Yu. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Попов Юрий Васильевич - доктор медицинских наук, профессор, заслуженный деятель науки РФ, главный научный сотрудник и научный руководитель отделения лечения психических расстройств у лиц молодого возраста.</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Popov Yuriy V. - PhD, Dr. Sc., Professor, Chief Researcher and Scientific Director of the Department of Treatment of Mental Disorders in Young People.</p><p>Saint Petersburg</p></bio><email xlink:type="simple">popov62@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Улитин</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Ulitin</surname><given-names>А. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Улитин Алексей Юрьевич - доктор медицинских наук, профессор, заслуженный врач РФ, директор.</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Ulitin Alexey Yu. - PhD, Dr. Sc., Director.</p><p>Saint Petersburg</p></bio><email xlink:type="simple">ulitinaleks@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр психиатрии и неврологии имени В.М. Бехтерева» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Institution «National Medical Research Center of Psychiatry and Neurology by V.M. Bekhterev» Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Российский научно-исследовательский нейрохирургический институт имени профессора А.Л. Поленова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Polenov Neurosurgical Institute</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>09</day><month>06</month><year>2019</year></pub-date><volume>6</volume><issue>2</issue><fpage>5</fpage><lpage>11</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шова Н.И., Михайлов В.А., Одинцова Г.В., Дружинин А.К., Попов Ю.В., Улитин А.Ю., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Шова Н.И., Михайлов В.А., Одинцова Г.В., Дружинин А.К., Попов Ю.В., Улитин А.Ю.</copyright-holder><copyright-holder xml:lang="en">Shova N.I., Mikhailov V.A., Odintsova G.V., Druzhinin A.K., Popov Y.V., Ulitin А.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://transmed.almazovcentre.ru/jour/article/view/459">https://transmed.almazovcentre.ru/jour/article/view/459</self-uri><abstract><p>Количество пациентов c эпилепсией и завершенной попыткой суицида в 5 раз выше, чем в общей популяции, и занимает третью позицию среди причин смерти в этой нозологической группе. Изучение психопатологических характеристик больных эпилепсией приближает нас к пониманию возможного суицидального поведения в этой группе пациентов. Особый интерес представляют больные с фармакорезистентной формой в послеоперационном периоде. Длительное течение заболевания и наличие «кризисной ситуации» как осознания факта оперативного лечения может деформировать внутреннюю картину болезни и на фоне изменений личности в послеоперационном периоде приводить к социальной дезадаптации, ухудшая прогноз заболевания, вплоть до возникновения суицидальных намерений. Учитывая клиническую значимость заболевания и высокую частоту психических нарушений при эпилепсии, в том числе возникающих после операции, лучшее понимание возможных суицидальных намерений может помочь в оптимизации социальной адаптации больных и превенции суицидов.</p></abstract><trans-abstract xml:lang="en"><p>The number of patients with epilepsy and completed attempt at suicide is 5 times higher than in the general population and ranks third among the causes of death in this group. Studying the psychopathological characteristics of patients with epilepsy brings us closer to an understanding of the possible suicidal behavior in this group of patients. Of particular interest are patients with pharmacoresistant form in the postoperative period. The long course of the disease and the presence of a “crisis situation”, as an awareness of the fact of operative treatment, can deform the internal picture of the disease and, against the background of personality changes in the postoperative period, lead to social disadaptation, worsening the prognosis of the disease, up to the occurrence of suicidal intentions. Given the clinical significance of the disease and the high incidence of mental disorders during epilepsy, including those that occur after surgery, a better understanding of possible suicidal intentions can help in optimizing the social adaptation of patients and the prevention of suicides.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>эпилепсия</kwd><kwd>риск суицида</kwd><kwd>непсихотические психические расстройства</kwd><kwd>оперативное лечение</kwd><kwd>фармакорезистентность</kwd><kwd>аффективные нарушения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>epilepsy</kwd><kwd>risk of suicide</kwd><kwd>non-psychotic mental disorders</kwd><kwd>operative treatment</kwd><kwd>pharmacoresis-tance</kwd><kwd>affective disorders</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Picot MC, Baldy-Moulinier M, Daures JP et al. 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