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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">transmed</journal-id><journal-title-group><journal-title xml:lang="ru">Трансляционная медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Translational Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2311-4495</issn><issn pub-type="epub">2410-5155</issn><publisher><publisher-name>Almazov National Medical Research Centre, Saint Petersburg, Russia</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18705/2311-4495-2014-0-2-47-51</article-id><article-id custom-type="elpub" pub-id-type="custom">transmed-23</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КАРДИОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CARDIOLOGY</subject></subj-group></article-categories><title-group><article-title>Клиническое течение инфаркта миокарда у больных с дисфункцией почек в стационаре</article-title><trans-title-group xml:lang="en"><trans-title>THE CLINICAL COURSE OF MYOCARDIAL INFARCTION IN PATIENTS WITH RENAL DYSFUNCTION IN HOSPITAL PERIOD</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Скородумова</surname><given-names>Елена Андреевна</given-names></name><name name-style="western" xml:lang="en"><surname>Skorodumova</surname><given-names>Elena A.</given-names></name></name-alternatives><email xlink:type="simple">elskor@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Костенко</surname><given-names>Виктор Авенирович</given-names></name><name name-style="western" xml:lang="en"><surname>Kostenko</surname><given-names>V. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фёдоров</surname><given-names>Артем Николаевич</given-names></name><name name-style="western" xml:lang="en"><surname>Fedorov</surname><given-names>A. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБУ «Санкт-Петербургский Научно-исследовательский институт скорой помощи им. проф. И.И. Джанелидзе»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Institute for Emergency Medical Care n.a. I.I. Dzhanelidze</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>23</day><month>12</month><year>2016</year></pub-date><volume>0</volume><issue>2</issue><fpage>47</fpage><lpage>51</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Скородумова Е.А., Костенко В.А., Фёдоров А.Н., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Скородумова Е.А., Костенко В.А., Фёдоров А.Н.</copyright-holder><copyright-holder xml:lang="en">Skorodumova E.A., Kostenko V.A., Fedorov A.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://transmed.almazovcentre.ru/jour/article/view/23">https://transmed.almazovcentre.ru/jour/article/view/23</self-uri><abstract><p>В статье представлены данные о влиянии хронической болезни почек (ХБП) на клиническое течение инфаркта миокарда (ИМ). В исследование включены 455 пациентов, лечившихся в Санкт-Петербургском ГБУ НИИ СП им. И.И. Джанелидзе с диагнозом «инфаркт миокарда». Больные разделены на 3 группы: в первой - пациенты с ХБП 1 ст., ХБП 2 ст. и без нее, во второй - с ХБП ст. 3а, в третьей - с ХБП ст. 3б. Показан достоверный рост частоты повторных ИМ, сердечной недостаточности, ранней постинфарктной стенокардии, рецидивов ИМ, нарушений сердечного ритма и летальности по мере увеличения степени тяжести ХБП. Пациенты с ОКС на фоне дисфункции почек требуют повышенного внимания и более частого контроля, а также особого учета нефротоксического эффекта лекарственных препаратов.</p></abstract><trans-abstract xml:lang="en"><p>The article presents data of the impact of chronic kidney disease (CKD) on the clinical course of myocardial infarction (MI). 455 patients with myocardial infarction observed at the St. Petersburg Research Institute for Emergency Medical Care were included in the study. The patients were divided into 3 groups. The first group involved patients with CKD stages 1 st., CKD stages 2 st. and without it, the second one with CKD 3a, and patients with CKD 3b were enrolled in the third group. We revealed significant elevation in the rate of reinfarction, heart failure, early postinfarction angina, recurrent MI, cardiac arrhythmia and mortality depending upon severity of renal dysfunction. Patients with MI and renal disorders require more attention, more frequent control and special consideration of medication's nephrotoxicity.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>инфаркт миокарда</kwd><kwd>хроническая болезнь почек</kwd><kwd>клиническое течение ИМ</kwd><kwd>myocardial infarction</kwd><kwd>chronic kidney disease</kwd><kwd>the clinical course of MI</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Шестакова М.В., Дедов И.И. Сахарный диабет и хроническая болезнь почек. - М.: Медицинское информационное агентство, 2009. - 482 с.</mixed-citation><mixed-citation xml:lang="en">Шестакова М.В., Дедов И.И. Сахарный диабет и хроническая болезнь почек. - М.: Медицинское информационное агентство, 2009. - 482 с.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Sarnak M.J., Levey A.S., Schoolwerth A.C. et al. Kidney disease as a risk factor for development of cardiovascular disease // Circulation. - 2003. - Vol. 108. - P. 2154-2169.</mixed-citation><mixed-citation xml:lang="en">Sarnak M.J., Levey A.S., Schoolwerth A.C. et al. Kidney disease as a risk factor for development of cardiovascular disease // Circulation. - 2003. - Vol. 108. - P. 2154-2169.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Coresh J., Astor B.C., Greene T. et al. Prevalence of chronic kidney disease and decreased kidney function in the adult US population. Third National Health and Nutrition Examination Survey // Am. J. Kidney Dis. - 2003. - Vol. 31. - P. 1-12.</mixed-citation><mixed-citation xml:lang="en">Coresh J., Astor B.C., Greene T. et al. Prevalence of chronic kidney disease and decreased kidney function in the adult US population. Third National Health and Nutrition Examination Survey // Am. J. Kidney Dis. - 2003. - Vol. 31. - P. 1-12.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Bhatt D.L., Roe M.T., Peterson E.D. et al. Utilization of early invasive management strategies for high-risk patients with non-ST-segment elevation acute coronary syndromes. Results from the CRUSADE Quality Improvement Initiative // JAMA. - 2004. - Vol. 292. - Р. 2096-2104.</mixed-citation><mixed-citation xml:lang="en">Bhatt D.L., Roe M.T., Peterson E.D. et al. Utilization of early invasive management strategies for high-risk patients with non-ST-segment elevation acute coronary syndromes. Results from the CRUSADE Quality Improvement Initiative // JAMA. - 2004. - Vol. 292. - Р. 2096-2104.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Das M., Aronow W.S., McClung J.A., Belkin R.N. Increased prevalence of coronary artery disease, silent myocardial ischemia, complex ventricular arrhythmias, atrial fibrillation, left ventricular hypertrophy, mitral annular calcium, and aortic valve calcium in patients with chronic renal insufficiency // Cardiol. Rev. - 2006. - Vol.14. - Р. 14-17.</mixed-citation><mixed-citation xml:lang="en">Das M., Aronow W.S., McClung J.A., Belkin R.N. Increased prevalence of coronary artery disease, silent myocardial ischemia, complex ventricular arrhythmias, atrial fibrillation, left ventricular hypertrophy, mitral annular calcium, and aortic valve calcium in patients with chronic renal insufficiency // Cardiol. Rev. - 2006. - Vol.14. - Р. 14-17.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Masoudi F.A., Plomondon M.E., Magid D.J. et al. Renal insufficiency and mortality from acute coronary syndromes // Am. Heart. J. - 2004. - Vol. 147, № 4. - P. 623-629.</mixed-citation><mixed-citation xml:lang="en">Masoudi F.A., Plomondon M.E., Magid D.J. et al. Renal insufficiency and mortality from acute coronary syndromes // Am. Heart. J. - 2004. - Vol. 147, № 4. - P. 623-629.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Gibson C.M., Pinto D.C., Murphy S.A. et al. Association of creatinine and creatinine clearance on presentation in acute myocardial infarction with subsequent mortality // JACC. - 2003. - Vol. 42. - P. 1535-1543.</mixed-citation><mixed-citation xml:lang="en">Gibson C.M., Pinto D.C., Murphy S.A. et al. Association of creatinine and creatinine clearance on presentation in acute myocardial infarction with subsequent mortality // JACC. - 2003. - Vol. 42. - P. 1535-1543.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Gibson C.M. et al. Association of glomerular filtration rate on presentation with subsequent mortality in non-ST-segment elevation acute coronary syndrome; observations in 13307 patients in five TIMI trials // Eur. Heart. J. - 2004. - Vol. 25, № 22. - P. 1998-2005.</mixed-citation><mixed-citation xml:lang="en">Gibson C.M. et al. Association of glomerular filtration rate on presentation with subsequent mortality in non-ST-segment elevation acute coronary syndrome; observations in 13307 patients in five TIMI trials // Eur. Heart. J. - 2004. - Vol. 25, № 22. - P. 1998-2005.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">National Kidney Foundation. K/DOQI Clinical Practice Guidelines for Chronic Kidney Disease: Evaluation, Classification, and Stratification // Am. J. Kidney Dis. - 2002. - Vol. 39, Suppl. 1. - P. Sl-266.</mixed-citation><mixed-citation xml:lang="en">National Kidney Foundation. K/DOQI Clinical Practice Guidelines for Chronic Kidney Disease: Evaluation, Classification, and Stratification // Am. J. Kidney Dis. - 2002. - Vol. 39, Suppl. 1. - P. Sl-266.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">CFR Calculators: Serum Creatinine and Cystatin С (2012). [Электронный ресурс]. URL: http://www.mdrd.com/ (дата обращения 11.02.2014).</mixed-citation><mixed-citation xml:lang="en">CFR Calculators: Serum Creatinine and Cystatin С (2012). [Электронный ресурс]. URL: http://www.mdrd.com/ (дата обращения 11.02.2014).</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Гублер Е.В. Вычислительные методы анализа и распознавания патологических процессов. - Л., 1978. - 86 с.</mixed-citation><mixed-citation xml:lang="en">Гублер Е.В. Вычислительные методы анализа и распознавания патологических процессов. - Л., 1978. - 86 с.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Николайчук Е.И., Бородзюля М.Э., Беркович О.А. Диагностические методы выявления нарушения функционирования почек у пациентов с ИБС и сердечной недостаточностью // Регионарное кровообращение и микроциркуляция. - 2008. - № 4. - С. 10-15.</mixed-citation><mixed-citation xml:lang="en">Николайчук Е.И., Бородзюля М.Э., Беркович О.А. Диагностические методы выявления нарушения функционирования почек у пациентов с ИБС и сердечной недостаточностью // Регионарное кровообращение и микроциркуляция. - 2008. - № 4. - С. 10-15.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Tessone A., Gottlieb S., Barbash I.M. et al. Underuse of Standard Care and Outcome of Patients with Acute Myocardial Infarction and Chronic Renal Insufficiency // Cardiology. - 2006. - Vol. 108, № 3. - P. 193-199.</mixed-citation><mixed-citation xml:lang="en">Tessone A., Gottlieb S., Barbash I.M. et al. Underuse of Standard Care and Outcome of Patients with Acute Myocardial Infarction and Chronic Renal Insufficiency // Cardiology. - 2006. - Vol. 108, № 3. - P. 193-199.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
