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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">transmed</journal-id><journal-title-group><journal-title xml:lang="ru">Трансляционная медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Translational Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2311-4495</issn><issn pub-type="epub">2410-5155</issn><publisher><publisher-name>Almazov National Medical Research Centre, Saint Petersburg, Russia</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18705/2311-4495-2016-3-4-14-19</article-id><article-id custom-type="elpub" pub-id-type="custom">transmed-203</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>РЕВМАТОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>RHEUMATOLOGY</subject></subj-group></article-categories><title-group><article-title>ВНУТРИСУСТАВНОЕ ВВЕДЕНИЕ ЛЕКАРСТВЕННЫХ ПРЕПАРАТОВ С УЛЬТРАЗВУКОВЫМ КОНТРОЛЕМ</article-title><trans-title-group xml:lang="en"><trans-title>INTRA-ARTICULAR INJECTION OF MEDICINAL PREPARATIONS WITH ULTRASOUND CONTROL</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Баженов</surname><given-names>Александр Николаевич</given-names></name><name name-style="western" xml:lang="en"><surname>Bazhenov</surname><given-names>A. N.</given-names></name></name-alternatives><email xlink:type="simple">bazhenov@almazovcentre.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Новикова</surname><given-names>Анна Николаевна</given-names></name><name name-style="western" xml:lang="en"><surname>Novikova</surname><given-names>A. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Баженова</surname><given-names>Ольга Петровна</given-names></name><name name-style="western" xml:lang="en"><surname>Bazhenova</surname><given-names>O. P.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Северо-Западный Федеральный медицинский исследовательский центр им. В. А. Алмазова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Almazov North-West Medical Research Centre</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>23</day><month>12</month><year>2016</year></pub-date><volume>3</volume><issue>4</issue><fpage>14</fpage><lpage>19</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Баженов А.Н., Новикова А.Н., Баженова О.П., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Баженов А.Н., Новикова А.Н., Баженова О.П.</copyright-holder><copyright-holder xml:lang="en">Bazhenov A.N., Novikova A.N., Bazhenova O.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://transmed.almazovcentre.ru/jour/article/view/203">https://transmed.almazovcentre.ru/jour/article/view/203</self-uri><abstract><p>В статье обсуждается эффективность и особенности внутрисуставного введения лекарственных препаратов, которое позволяет уменьшить дозу пероральных препаратов, уменьшить вероятность побочных эффектов системной терапии. Внутрисуставное введение препаратов с ультразвуковым контролем повышает точность введения, снижает риск развития осложнений при проведении инъекций. Растущий спрос на указанные манипуляции увеличивает потребность в новых устройствах и приспособлениях для осуществления внутрисуставных инъекций, стимулирует их разработку.</p></abstract><trans-abstract xml:lang="en"><p>The article discusses the effectiveness and features of intra-articular injection of medical preparations, which makes it possible to reduce the dose of oral medication, reduce the likelihood of side effects of systemic therapy. Intra-articular injection of drugs with ultrasound control improves the accuracy of injection, reduces the risk of complications when performing injections. The growing request for these manipulations increases the need for new devices and appliances for implementation of intra-articular injection to stimulate their development.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>Внутрисуставная инъекция</kwd><kwd>глюкокортикоид</kwd><kwd>гиалуроновая кислота</kwd><kwd>остеоартроз</kwd><kwd>ультразвуковой контроль</kwd><kwd>intra-articular injection</kwd><kwd>steroid</kwd><kwd>hyaluronic acid</kwd><kwd>osteoarthritis</kwd><kwd>ultrasonic testing</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Инъекции в суставы верхних и нижних конечностей под ультразвуковым контролем. http://rh.org.ru/news/152-in-ektsii-v-sustavy-verkhnikh-i-nizhnikh-konechnostej-pod-ultrazvukovym-kontrolem</mixed-citation><mixed-citation xml:lang="en">Инъекции в суставы верхних и нижних конечностей под ультразвуковым контролем. http://rh.org.ru/news/152-in-ektsii-v-sustavy-verkhnikh-i-nizhnikh-konechnostej-pod-ultrazvukovym-kontrolem</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Van Middelkoop M, Arden N.K, Atchia I, et al. The OA Trial Bank: Meta-analysis of individual patient data from knee and hip osteoarthritis trials show that patients with severe pain exhibit greater benefit from intra-articular glucocorticoids. Osteoarthritis Cartilage. 2016; 24(7):1143-52.</mixed-citation><mixed-citation xml:lang="en">Van Middelkoop M, Arden N.K, Atchia I, et al. The OA Trial Bank: Meta-analysis of individual patient data from knee and hip osteoarthritis trials show that patients with severe pain exhibit greater benefit from intra-articular glucocorticoids. Osteoarthritis Cartilage. 2016; 24(7):1143-52.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Henricsdotter C, Ellegaard K, Klokker L, Bartholdy C, Bandak E, Bartels E.M, Bliddal H, Henriksen M. Changes in ultrasound assessed markers of inflammation following intra-articular steroid injection combined with exercise in knee osteoarthritis: exploratory outcome from a randomized trial. Osteoarthritis Cartilage. 2016;24(5):814-21.</mixed-citation><mixed-citation xml:lang="en">Henricsdotter C, Ellegaard K, Klokker L, Bartholdy C, Bandak E, Bartels E.M, Bliddal H, Henriksen M. Changes in ultrasound assessed markers of inflammation following intra-articular steroid injection combined with exercise in knee osteoarthritis: exploratory outcome from a randomized trial. Osteoarthritis Cartilage. 2016;24(5):814-21.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Rivera F, Bertignone L, Grandi G, Camisassa R, Comaschi G, Trentini D, Zanone M, Teppex G, Vasario G, Fortina G. Effectiveness of intra-articular injections of sodium hyaluronate-chondroitin sulfate in knee osteoarthritis: a multicenter prospective study. J Orthop Traumatol. 2016;17(1):27-33.</mixed-citation><mixed-citation xml:lang="en">Rivera F, Bertignone L, Grandi G, Camisassa R, Comaschi G, Trentini D, Zanone M, Teppex G, Vasario G, Fortina G. Effectiveness of intra-articular injections of sodium hyaluronate-chondroitin sulfate in knee osteoarthritis: a multicenter prospective study. J Orthop Traumatol. 2016;17(1):27-33.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Bruyère O, Cooper C, Pelletier J.P, Maheu E, Rannou F, Branco J, Luisa Brandi M, Kanis J.A, Altman R.D, Hochberg M.C, Martel-Pelletier J, Reginster JY A consensus statement on the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) algorithm for the management of knee osteoarthritis-From evidence-based medicine to the real-life setting. Semin Arthritis Rheum. 2016;45(4 Suppl):S3-11.</mixed-citation><mixed-citation xml:lang="en">Bruyère O, Cooper C, Pelletier J.P, Maheu E, Rannou F, Branco J, Luisa Brandi M, Kanis J.A, Altman R.D, Hochberg M.C, Martel-Pelletier J, Reginster JY A consensus statement on the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) algorithm for the management of knee osteoarthritis-From evidence-based medicine to the real-life setting. Semin Arthritis Rheum. 2016;45(4 Suppl):S3-11.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Maheu E, Rannou F, Reginster J.Y. Efficacy and safety of hyaluronic acid in the management of osteoarthritis: Evidence from real-life setting trials and surveys. Semin Arthritis Rheum. 2016;45(4 Suppl):S28-33.</mixed-citation><mixed-citation xml:lang="en">Maheu E, Rannou F, Reginster J.Y. Efficacy and safety of hyaluronic acid in the management of osteoarthritis: Evidence from real-life setting trials and surveys. Semin Arthritis Rheum. 2016;45(4 Suppl):S28-33.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Chapelle Ch. Intra-articular injections. [Article in French]. Rev Med Brux. 2015; 36(4): 281-287.</mixed-citation><mixed-citation xml:lang="en">Chapelle Ch. Intra-articular injections. [Article in French]. Rev Med Brux. 2015; 36(4): 281-287.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Saccomanno M.F, Donati F, Careri S, Bartoli M, Severini G, Milano G. Efficacy of intra-articular hyaluronic acid injections and exercise-based rehabilitation programme, administered as isolated or integrated therapeutic regimens for the treatment of knee osteoarthritis. Knee Surg Sports Traumatol Arthrosc. 2016;24(5):1686-94.</mixed-citation><mixed-citation xml:lang="en">Saccomanno M.F, Donati F, Careri S, Bartoli M, Severini G, Milano G. Efficacy of intra-articular hyaluronic acid injections and exercise-based rehabilitation programme, administered as isolated or integrated therapeutic regimens for the treatment of knee osteoarthritis. Knee Surg Sports Traumatol Arthrosc. 2016;24(5):1686-94.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Trojian T.H, Concoff A.L, Joy S.M, et al. AMSSM scientific statement concerning viscosupplementation in jections for knee osteoarthritis: importance for individual patient outcomes. Br J Sports Med. 2016; 50(2): 84-92.</mixed-citation><mixed-citation xml:lang="en">Trojian T.H, Concoff A.L, Joy S.M, et al. AMSSM scientific statement concerning viscosupplementation in jections for knee osteoarthritis: importance for individual patient outcomes. Br J Sports Med. 2016; 50(2): 84-92.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Baselga Garria-Escudero J, Miguel Hernandez Trillos P. Treatment of Osteoarthritis of the Knee with a Combination of Autologous Conditioned Serum and Physiotherapy: A Two-Year Observational Study. PLoS One. 2015; 10(12): e0145551.</mixed-citation><mixed-citation xml:lang="en">Baselga Garria-Escudero J, Miguel Hernandez Trillos P. Treatment of Osteoarthritis of the Knee with a Combination of Autologous Conditioned Serum and Physiotherapy: A Two-Year Observational Study. PLoS One. 2015; 10(12): e0145551.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Smith P.A. Intra-articular Autologous Conditioned Plasma Injections Provide Safe and Efficacious Treatment for Knee Osteoarthritis: An FDA-Sanctioned, Randomized, Double-blind, Placebo-controlled Clinical Trial. Am J Sports Med. 2016;44(4):884-91.</mixed-citation><mixed-citation xml:lang="en">Smith P.A. Intra-articular Autologous Conditioned Plasma Injections Provide Safe and Efficacious Treatment for Knee Osteoarthritis: An FDA-Sanctioned, Randomized, Double-blind, Placebo-controlled Clinical Trial. Am J Sports Med. 2016;44(4):884-91.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Ling B.C, Lee J.W, Man H.S, et al. Transverse morphology of the sacroiliac joint: effect of angulation and implications for fluoroscopically guided sacroiliac joint injection. Skeletal Radiol. 2006; 35(11): 838-846.</mixed-citation><mixed-citation xml:lang="en">Ling B.C, Lee J.W, Man H.S, et al. Transverse morphology of the sacroiliac joint: effect of angulation and implications for fluoroscopically guided sacroiliac joint injection. Skeletal Radiol. 2006; 35(11): 838-846.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Küllmer K, Rompe J.D, Löwe A, et al. Ultrasound image of the lumbar spine and the lumbosacral transition. Ultrasound anatomy and possibilities for ultrasonically-controlled facet joint infiltration [Article in German]. Z Orthop Ihre Grenzgeb. 1997; 135(4): 310-314.</mixed-citation><mixed-citation xml:lang="en">Küllmer K, Rompe J.D, Löwe A, et al. Ultrasound image of the lumbar spine and the lumbosacral transition. Ultrasound anatomy and possibilities for ultrasonically-controlled facet joint infiltration [Article in German]. Z Orthop Ihre Grenzgeb. 1997; 135(4): 310-314.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">McCormick Z.L, Cushman D, Lee D.T, Scholten P, Chu S.K, Babu A.N, Caldwell M, Ziegler C, Ashraf H, Sundar B, Clark R, Gross C, Cara J, McCormick K, Ross B, Smith C.C, Press J, Smuck M, Walega D.R. Is There a Relationship Between Body Mass Index and Fluoroscopy Time During Sacroiliac Joint Injection? A Multicenter Cohort Study. Pain Med. 2016;17(7):1241-1248.</mixed-citation><mixed-citation xml:lang="en">McCormick Z.L, Cushman D, Lee D.T, Scholten P, Chu S.K, Babu A.N, Caldwell M, Ziegler C, Ashraf H, Sundar B, Clark R, Gross C, Cara J, McCormick K, Ross B, Smith C.C, Press J, Smuck M, Walega D.R. Is There a Relationship Between Body Mass Index and Fluoroscopy Time During Sacroiliac Joint Injection? A Multicenter Cohort Study. Pain Med. 2016;17(7):1241-1248.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Dallari D, Stagni C, Rani N, et al. Ultrasound-Guided Injection of Platelet-Rich Plasma and Hyaluronic Acid, Separately and in Combination, for Hip Osteoarthritis: A Randomized Controlled Study. Am J Sports Med. 2016; 44(3): 664-71.</mixed-citation><mixed-citation xml:lang="en">Dallari D, Stagni C, Rani N, et al. Ultrasound-Guided Injection of Platelet-Rich Plasma and Hyaluronic Acid, Separately and in Combination, for Hip Osteoarthritis: A Randomized Controlled Study. Am J Sports Med. 2016; 44(3): 664-71.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Баженов А.Н., Баженова О.П. Насадка для инъекций под ультразвуковым контролем. Патент по заявке № 2012156771 от 25.12.2012</mixed-citation><mixed-citation xml:lang="en">Баженов А.Н., Баженова О.П. Насадка для инъекций под ультразвуковым контролем. Патент по заявке № 2012156771 от 25.12.2012</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Баженов А.Н., Баженова О.П. Устройство для инъекций под ультразвуковым контролем (варианты). Патент по заявке № 2016112460 от 01.04.2016 г.</mixed-citation><mixed-citation xml:lang="en">Баженов А.Н., Баженова О.П. Устройство для инъекций под ультразвуковым контролем (варианты). Патент по заявке № 2016112460 от 01.04.2016 г.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
