transmedТрансляционная медицинаTranslational Medicine2311-44952410-5155Almazov National Medical Research Centre, Saint Petersburg, Russia10.18705/2311-4495-2016-3-3-34-41transmed-187Research ArticleОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯORIGINAL RESEARCHГендерные особенности интервенционного лечения фибрилляции предсердий: проспективное исследование эффективности, безопасности вмешательства и качества жизни пациентовGender aspects in catheter ablation of atrial fibrillation: a prospective study of efficacy, safety of the procedure and quality of life of the patientsПацюкАнна ВладимировнаPatsyukAnna V.patsouk@yandex.ruАбрамовМихаил ЛеонидовичAbramovMikhail L.noemail@neicon.ruЛебедевДмитрий СергеевичLebedevDmitrii S.noemail@neicon.ruМихайловЕвгений НиколаевичMikhaylovEvgeniy N.noemail@neicon.ruФГБУ «СЗФМИЦ им. В.А. Алмазова» Минздрава РоссииРоссияFederal Almazov North-West Medical Research CentreRussian FederationФГБУ «СЗФМИЦ им. В.А. Алмазова» Минздрава РоссииРоссияDepartment of arrhythmology Federal Almazov North-West Medical Research CentreRussian Federation201623122016333441Copyright © Пацюк А.В., Абрамов М.Л., Лебедев Д.С., Михайлов Е.Н., 20162016Пацюк А.В., Абрамов М.Л., Лебедев Д.С., Михайлов Е.Н.Patsyuk A.V., Abramov M.L., Lebedev D.S., Mikhaylov E.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://transmed.almazovcentre.ru/jour/article/view/187

Фибрилляция предсердий (ФП) является наиболее распространенным видом нарушений ритма сердца. Различия в эффективности и безопасности катетерного лечения ФП у мужчин и женщин остаются малоизученными. Цель исследования - выявить гендерные различия у пациентов с ФП, направленных на катетерную аблацию. Методы: в проспективное исследование было включено 55 пациентов с ФП (25 мужчин), направленных на радиочастотную изоляцию ЛВ. Сравнивались: ФВ левого желудочка, диаметр ЛП, КЖ, EHRA score и эффективность до и после аблации. Результаты. Частота рецидивов составила 28 % у мужчин и 40 % у женщин. Перед аблацией женщины имели более низкие психологические параметры КЖ, чем мужчины (15,9 против 19,9, р < 0,05) и более выраженные симптомы. У женщин чаще встречались интра- и послеоперационные осложнения (12 % женщин и 5 % мужчин, p > 0,05). У всех пациентов без рецидивов ФП отмечалось улучшение КЖ и уменьшение клинической симптоматики. Выводы. Не выявлено влияние пола на эффективность катетерной аблации. Однако у женщин выраженная симптомность ФП ассоциирована с низкими психологическими параметрами качества жизни. КЖ может быть одним из показателей эффективности КА.

Background. Atrial fibrillation (AF) is the most common type of cardiac arrhythmia. There is paucity of information regarding gender differences in outcomes of patients undergoing AF catheter ablation. The aim of this prospective study was to determine gender differences in clinical characteristics, quality of life (QoL) and outcomes of the patients referred for AF catheter ablation. Methods. The study comprised of 55 patients (25 men) with symptomatic AF, who were referred for pulmonary vein isolation. A variety of clinical characteristics, echocardiography parameters, QoL before and after catheter ablation, safety and efficacy of the procedure over 12-months follow-up period were compared between men and women. Results. At the baseline, women had lower values of psychological parameters of QoL comparing to men (15,9 vs 19,9, p < 0.05), and more severe symptoms. Within 12 months after the procedure arrhythmia recurred in 28 % men and in 40 % women. Women had more complications during the procedure and in early postablation period (12 % women and 5 % men, p < 0.05). All patients with no arrhythmia recurrence had a significant improvement in all QoL domains and a decrease in AF EHRA score. Conclusions. The psychological status of women with AF associated with high degree of clinical manifestations. QOL can be an indicator of the efficacy of catheter ablation.

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The authors declare that there are no conflicts of interest present.