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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">transmed</journal-id><journal-title-group><journal-title xml:lang="ru">Трансляционная медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Translational Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2311-4495</issn><issn pub-type="epub">2410-5155</issn><publisher><publisher-name>Almazov National Medical Research Centre, Saint Petersburg, Russia</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18705/2311-4495-2016-3-2-31-39</article-id><article-id custom-type="elpub" pub-id-type="custom">transmed-175</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КАРДИОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CARDIOLOGY</subject></subj-group></article-categories><title-group><article-title>ФУНКЦИОНАЛЬНОЕ СОСТОЯНИЕ ПОЧЕК И КЛИНИКО-АНАМНЕСТИЧЕСКИЕ ДАННЫЕ ПРИ ОСТРОЙ И ХРОНИЧЕСКОЙ ИШЕМИЧЕСКОЙ БОЛЕЗНИ СЕРДЦА (ФРАГМЕНТ ИССЛЕДОВАНИЯ РОКСИМ-УЗ)</article-title><trans-title-group xml:lang="en"><trans-title>RENAL FUNCTION, CLINICAL AND MEDICAL HISTORY DATA IN ACUTE AND CHRONIC ISCHEMIC HEART DISEASE (FRAGMENT OF RESEARCH RACSMI-UZ)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нагаева</surname><given-names>Гульнора Анваровна</given-names></name><name name-style="western" xml:lang="en"><surname>Nagaeva</surname><given-names>Gulnora A.</given-names></name></name-alternatives><email xlink:type="simple">nagaeva.gulnora@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мамутов</surname><given-names>Рефат Шукриевич</given-names></name><name name-style="western" xml:lang="en"><surname>Mamutov</surname><given-names>Refat Sh.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>АО «Республиканский специализированный центр кардиологии»</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>23</day><month>12</month><year>2016</year></pub-date><volume>3</volume><issue>2</issue><fpage>31</fpage><lpage>39</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Нагаева Г.А., Мамутов Р.Ш., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Нагаева Г.А., Мамутов Р.Ш.</copyright-holder><copyright-holder xml:lang="en">Nagaeva G.A., Mamutov R.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://transmed.almazovcentre.ru/jour/article/view/175">https://transmed.almazovcentre.ru/jour/article/view/175</self-uri><abstract><p>В данной статье представлены предварительные результаты исследования РОКСИМ-Уз, проводящегося в данный момент в одном из районов г. Ташкента. Цель настоящего исследования - оценка функционального состояния почек и клинико-анамнестических данных у больных с острым коронарным синдромом и острым инфарктом миокарда (ОКС/ОИМ) в экспериментальном районе г. Ташкента. В данном фрагменте исследования проанализированы данные 67 больных, госпитализированных в соответствующие ЛПУ экспериментального района г. Ташкента с диагнозом ОКС/ОИМ за период с 01.01.2015 по 01.10.2015 года. По мере проводимого стационарного лечения и стабилизации состояния конфигурация диагнозов менялась. В зависимости от этого больные были разделены на две группы: 1 гр. - 32 больных, которые в выписном эпикризе имели диагноз ОИМ с/без Q, и 2 гр. - 35 больных, у которых в выписках фиксировалась стабильная стенокардия напряжения II-III функционального класса (ФК). Анализ анамнестических данных установил, что перенесенный ОИМ и чрескожные вмешательства (ЧКВ), а также наличие сопутствующих хронической почечной недостаточности и сахарного диабета 2 типа, являлись прерогативой лиц с острой формой ИБС, в то время как для пациентов со стабильным течением заболевания было характерно наличие венечных стенозов свыше 50 % и перенесенные аортокоронарные шунтирования (АКШ); наиболее часто принимаемыми на амбулаторном этапе группами препаратов оказались β-адреноблокаторы и ацетилсалициловая кислота, однако количественный суточный рацион лекарственных средств более чем в 1,5 раза был выше у больных со стабильной ИБС. Пациенты с ОИМ с/без Q имели сравнительно низкие значения липидного спектра крови и повышенный уровень коэффициента де Ритиса. Несмотря на то, что скорость клубочковой фильтрации была сопоставима в обеих группах пациентов, тем не менее терминальная стадия хронической болезни почек оказалась прерогативой респондентов с острым течением заболевания.</p></abstract><trans-abstract xml:lang="en"><p>This article presents the preliminary results of the study (RACSMI-Uz) conducting at the moment in one of Tashkent districts. The purpose of this study is assessment of renal function and clinical and anamnesis in patients with acute coronary syndrome and acute myocardial infarction (ACS / MI) in the experimental area of the city of Tashkent. In this fragment the study analyzed the data of 67 patients admitted to the relevant medical institutions of the pilot district of Tashkent with a diagnosis of ACS / AMI for the period from 01.01.2015 to 01.10.2015 year. As the ongoing hospital treatment and stabilization diagnoses configuration changed. Depending on this, the patients were divided into two groups: 1g. - 32 patients who had a diagnosis of the discharge summary AMI with / without Q and 2g. - 35 patients who was recorded in extracts from hospital the stable exertional angina II-III functional class (FC). Analysis of anamnestic data found that myocardial infarction and percutaneous coronary intervention (PCI), as well as the presence of concomitant chronic kidney disease and type 2 diabetes mellitus were the prerogative of individuals with acute coronary artery disease, whereas for patients with stable disease was characterized by the presence of coronary stenoses more than 50% and transferred coronary artery bypass grafting (CABG); most often taken on outpatient drugs groups were β-blockers and acetylsalicylic acid, however, quantitative daily diet drugs more than 1,5 times was higher in patients with stable coronary artery disease. Patients with AMI with / without Q have relatively low values of the lipid spectrum of the blood and elevated levels of factor de Rytis. Despite the fact that the glomerular filtration rate was comparable in both groups of patients, however, end-stage chronic renal disease was the prerogative of the respondents with acute course of disease.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>острый коронарный синдром</kwd><kwd>острый инфаркт миокарда</kwd><kwd>скорость клубочковой фильтрации</kwd><kwd>гипертриглицеридемия</kwd><kwd>acute coronary syndrome</kwd><kwd>acute myocardial infarction</kwd><kwd>glomerular filtration rate</kwd><kwd>hypertriglyceridemia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">The Committee of experts RSSC. National guidelines for the diagnosis and treatment of patients with acute myocardial infarction with ST-segment elevation of the ECG. 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Pol Arch Med Wewn. 2009;119 (7-8): 487-492.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
