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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">transmed</journal-id><journal-title-group><journal-title xml:lang="ru">Трансляционная медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Translational Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2311-4495</issn><issn pub-type="epub">2410-5155</issn><publisher><publisher-name>Almazov National Medical Research Centre, Saint Petersburg, Russia</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18705/2311-4495-2025-12-5-503-511</article-id><article-id custom-type="edn" pub-id-type="custom">YTAAEM</article-id><article-id custom-type="elpub" pub-id-type="custom">transmed-1054</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НЕВРОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>NEUROLOGY</subject></subj-group></article-categories><title-group><article-title>Результаты хирургического лечения синдрома карпального канала.  Опыт Центра Алмазова</article-title><trans-title-group xml:lang="en"><trans-title>Results of surgical treatment of carpal tunnel syndrome.   Experience of Almazov Centre</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4431-375X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Городнина</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gorodnina</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Городнина Ангелина Викторовна — кандидат медицинских наук, врач-нейрохирург нейрохирургического отделения № 1</p><p>ул. Аккуратова, д. 2, Санкт-Петербург, 197341</p></bio><bio xml:lang="en"><p>Angelina V. Gorodnina, MD, PhD, neurosurgeon, neurosurgical department No. 1</p><p>Akkuratova str., 2, St. Petersburg,197341</p></bio><email xlink:type="simple">angelinagorodnina@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Очинский</surname><given-names>Д. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Ochinsky</surname><given-names>D. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Очинский Дмитрий Юрьевич — врач-невролог</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Dmitry Yu. Ochinsky, MD, neurologist</p><p>St. Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Овчинников</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ovchinnikov</surname><given-names>D. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Овчинников Дмитрий Александрович — врач-невролог</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Dmitry A. Ovchinnikov, MD, neurologist</p><p>St. Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное учреждение &#13;
«Национальный медицинский исследовательский центр имени  &#13;
В. А. Алмазова» Министерства здравоохранения Российской &#13;
Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Almazov National Medical Research Centre</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>13</day><month>01</month><year>2026</year></pub-date><volume>12</volume><issue>5</issue><elocation-id>503- 511</elocation-id><permissions><copyright-statement>Copyright &amp;#x00A9; Городнина А.В., Очинский Д.Ю., Овчинников Д.А., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Городнина А.В., Очинский Д.Ю., Овчинников Д.А.</copyright-holder><copyright-holder xml:lang="en">Gorodnina A.V., Ochinsky D.Y., Ovchinnikov D.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://transmed.almazovcentre.ru/jour/article/view/1054">https://transmed.almazovcentre.ru/jour/article/view/1054</self-uri><abstract><sec><title>Актуальность</title><p>Актуальность. Синдром карпального канала (СКК) представляет собой наиболее распространенную компрессионно-ишемическую нейропатию верхних конечностей, обладающую серьезным медико-социальным значением вследствие выраженного снижения трудоспособности пациентов различных возрастных групп.</p></sec><sec><title>Цель исследования</title><p>Цель исследования. Оценить результаты хирургического лечения пациентов с СКК методом минимально инвазивной открытой декомпрессии срединного нерва в карпальном канале.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. В исследование включены 107 пациентов с диагнозом СКК в возрасте от 33 до 88 лет. Все оперативные вмешательства выполнены амбулаторно в условиях местной анестезии. Клинические результаты оценивали с помощью объективного осмотра и анкетирования пациентов с использованием Бостонского опросника для оценки тяжести симптомов (SSS) и функциональных нарушений (FSS).</p></sec><sec><title>Результаты</title><p>Результаты. В подавляющем большинстве случаев регресс клинических симптомов отмечался уже на 14-й день после операции. До хирургического вмешательства средние значения SSS и FSS составляли 3,61±0,56 и 3,75±0,56 соответственно. После операции наблюдалось статистически значимое снижение показателей: среднее значение SSS уменьшилось до 1,16±0,04, а FSS — до 1,07±0,07 (p&lt;0,05).</p></sec><sec><title>Заключение</title><p>Заключение. Хирургическое лечение остается наиболее эффективным методом терапии синдрома карпального канала. Несмотря на разнообразие хирургических техник, минимизация операционной травмы при обеспечении адекватной декомпрессии срединного нерва является ключевой задачей для оптимизации клинических исходов и улучшения качества жизни пациентов.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Background</title><p>Background. Carpal tunnel syndrome (CTS) is the most common compression-ischemic neuropathy of the upper extremities, with significant medical and social significance due to the significant reduction in work capacity of patients of various age groups.</p></sec><sec><title>Study Objective</title><p>Study Objective. To evaluate the outcomes of surgical treatment of patients with CTS using minimally invasive open decompression of the median nerve in the carpal tunnel.</p></sec><sec><title>Materials and Methods</title><p>Materials and Methods. The study included 107 patients diagnosed with CTS, aged 33 to 88 years. All surgical procedures were performed on an outpatient basis under local anesthesia. Clinical outcomes were assessed using an objective examination and patient questionnaires using the Boston Symptom Severity Questionnaire (BSS) and the Functional Disability Questionnaire (FSS).</p></sec><sec><title>Results</title><p>Results. In the vast majority of cases, regression of clinical symptoms was noted as early as 14 days after surgery. Before surgery, the mean SSS and FSS values were 3.61±0.56 and 3.75±0.56, respectively. Postoperatively, a statistically significant reduction in these values was observed: the mean SSS decreased to 1.16±0.04, and the FSS decreased to 1.07±0.07 (p&lt;0.05).Conclusion. Surgical treatment remains the most effective method for treating carpal tunnel syndrome. Despite the variety of surgical techniques, minimizing surgical trauma while ensuring adequate decompression of the median nerve is key to optimizing clinical outcomes and improving patients’ quality of life.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>синдром карпального канала</kwd><kwd>декомпрессия срединного нерва</kwd><kwd>туннельный карпальный синдром</kwd><kwd>минимально инвазивная хирургия</kwd><kwd>амбулаторная хирургия кисти</kwd><kwd>открытая декомпрессия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>carpal tunnel syndrome</kwd><kwd>median nerve decompression</kwd><kwd>carpal tunnel syndrome</kwd><kwd>minimally invasive surgery</kwd><kwd>ambulatory hand surgery</kwd><kwd>open decompression</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Киселев В. Н., Борода А. Ю., Декан В. С., Ярушкина О. Е. 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