<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">transmed</journal-id><journal-title-group><journal-title xml:lang="ru">Трансляционная медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Translational Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2311-4495</issn><issn pub-type="epub">2410-5155</issn><publisher><publisher-name>Almazov National Medical Research Centre, Saint Petersburg, Russia</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18705/2311-4495-2015-0-6-25-31</article-id><article-id custom-type="elpub" pub-id-type="custom">transmed-102</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЭНДОКРИНОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ENDOCRINOLOGY</subject></subj-group></article-categories><title-group><article-title>Особенности дентальной имплантации у пациентов с сахарным диабетом</article-title><trans-title-group xml:lang="en"><trans-title>Dental implant treatment features in patients with diabetes mellitus</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никитин</surname><given-names>В. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikitin</surname><given-names>V. .</given-names></name></name-alternatives><email xlink:type="simple">nшkitin0709@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Капитонова</surname><given-names>О. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Kapitonova</surname><given-names>O. .</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Антонова</surname><given-names>И. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Antonova</surname><given-names>I. .</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Стоматологическая клиника «Выбор»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Dental clinic “Choice”</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБОУ ВПО «Первый Санкт-Петербургский государственный медицинский университет им. акад. И. П. Павлова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pavlov Fiest Saint-Petersburg State Medical Universit</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>23</day><month>12</month><year>2016</year></pub-date><volume>0</volume><issue>6</issue><fpage>25</fpage><lpage>31</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Никитин В.С., Капитонова О.П., Антонова И.Н., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Никитин В.С., Капитонова О.П., Антонова И.Н.</copyright-holder><copyright-holder xml:lang="en">Nikitin V..., Kapitonova O..., Antonova I...</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://transmed.almazovcentre.ru/jour/article/view/102">https://transmed.almazovcentre.ru/jour/article/view/102</self-uri><abstract><p>К числу наиболее значимых соматических заболеваний, определяющих протокол ведения стоматол-гических больных и стойкость долгосрочного функционирования протезов, относится сахарный диабет. В данной статье проведен обзор данных о морфологии, гистологических особенностях остеоинтеграции дентальных имплантатов у пациентов в сданной патологией, а так же анализ имеющихся проспективных и ретроспективных исследований в данной области.</p></abstract><trans-abstract xml:lang="en"><p>Diabetes mellitus is the one of the most important diseases, that affects survival of dental implants. This is an analytic article, that observe morphology, physiology, histology of osteointegration of dental implants in patients with diabetes mellitus. Also there are review of prospective and retrospective studies of this problem, that have been made. By the way most authors declares that success of prostodontic treatment in this patints composed of many factors such like original clinical situation, type of diabetes mellitus and degree of compensation ofthe disease and the last, but not the least, the design of contemporary prothetic restoration.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>дентальная имплантация</kwd><kwd>протезирование на имплантатах</kwd><kwd>протезирование с опорой на имплантаты</kwd><kwd>сахарный диабет</kwd><kwd>dental implantation</kwd><kwd>contemporary dental implant restoration</kwd><kwd>diabetes mellitus</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Mish CE. Dental education: meeting the demands of implant dentistry, J Am Dent Assoc 1990; 121:334-338.</mixed-citation><mixed-citation xml:lang="en">Mish CE. Dental education: meeting the demands of implant dentistry, J Am Dent Assoc 1990; 121:334-338.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Report of the Expert Committee on Diagnosis and Classification of Diabetes Mellitus, Diabetes care 1997; 20(7):1183-1197.</mixed-citation><mixed-citation xml:lang="en">Report of the Expert Committee on Diagnosis and Classification of Diabetes Mellitus, Diabetes care 1997; 20(7):1183-1197.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">King H, Aubert Re, Herman WH. Global burden of diabetes 1995-2025. Prevalence, numerical estimates and projections, Diabetes Care 1998; 21(9):1414-1431.</mixed-citation><mixed-citation xml:lang="en">King H, Aubert Re, Herman WH. Global burden of diabetes 1995-2025. Prevalence, numerical estimates and projections, Diabetes Care 1998; 21(9):1414-1431.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Franklin GM, Kahn LB, Baxter J et al. Sensory neuropathy in non-insulin-dependent diabetes: The San Luis Valley Diabetes Study, Am J Epidemiol 1990;131(4):633-643.</mixed-citation><mixed-citation xml:lang="en">Franklin GM, Kahn LB, Baxter J et al. Sensory neuropathy in non-insulin-dependent diabetes: The San Luis Valley Diabetes Study, Am J Epidemiol 1990;131(4):633-643.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Harris MI. Diabetes in America: Epidemiology and scope of the problem, Diabetes Care 21(Suppl 3) 1998; C11-14.</mixed-citation><mixed-citation xml:lang="en">Harris MI. Diabetes in America: Epidemiology and scope of the problem, Diabetes Care 21(Suppl 3) 1998; C11-14.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Peters Harmel A, Mathur R. Diabetes mellitus diagnosis and threatment. Elsevier, 2004: 496.</mixed-citation><mixed-citation xml:lang="en">Peters Harmel A, Mathur R. Diabetes mellitus diagnosis and threatment. Elsevier, 2004: 496.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Coutinho M, Gerstein HC, Wang Y et al. The relationship between glucose and incident cardiovascular events: A meta regression analysis of published data from 20 studies of 95,783 individuals followed for 12,4 years. Diabetes Care 1999; 22 (2): 233-240.</mixed-citation><mixed-citation xml:lang="en">Coutinho M, Gerstein HC, Wang Y et al. The relationship between glucose and incident cardiovascular events: A meta regression analysis of published data from 20 studies of 95,783 individuals followed for 12,4 years. Diabetes Care 1999; 22 (2): 233-240.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Wild SH, Dunn CJ, McKeigue PM. Et al. Glycemic control and cardiovascular disease in type 2 diabetes: A review. Diabetes Metab Res Rev 1999; 15 (3): 197-204.</mixed-citation><mixed-citation xml:lang="en">Wild SH, Dunn CJ, McKeigue PM. Et al. Glycemic control and cardiovascular disease in type 2 diabetes: A review. Diabetes Metab Res Rev 1999; 15 (3): 197-204.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Lim S, Tai ES, Tan BY. Cardiovascular risk profile in individuals with borderline glycemia. The effect of the 1997 American Diabetes Association diagnostic criteria and the 1998 World Health Organization provisional report. Diabetes Care 2000; 23 (3): 278-282.</mixed-citation><mixed-citation xml:lang="en">Lim S, Tai ES, Tan BY. Cardiovascular risk profile in individuals with borderline glycemia. The effect of the 1997 American Diabetes Association diagnostic criteria and the 1998 World Health Organization provisional report. Diabetes Care 2000; 23 (3): 278-282.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Alberti KG, Zimmer PZ. Definition, Diagnosis and Classification of Diabetes Mellitus and its Complications. Report of a WHO Consultation. Part I: Diabetes and Classification of Diabetes Mellitus WHO consultation. Diabet Med 1998; 16 (7): 539-553.</mixed-citation><mixed-citation xml:lang="en">Alberti KG, Zimmer PZ. Definition, Diagnosis and Classification of Diabetes Mellitus and its Complications. Report of a WHO Consultation. Part I: Diabetes and Classification of Diabetes Mellitus WHO consultation. Diabet Med 1998; 16 (7): 539-553.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Reva GV., Tolmachev VE, Pervov YY, Rusakova EY, Reva IV, Usov VV et al. An experience of dental implantation in patients with parodontal inflammatory diseases with local immune homeostasis control. Fundamental Researches. 2013; 5 (1): 129-134.</mixed-citation><mixed-citation xml:lang="en">Reva GV., Tolmachev VE, Pervov YY, Rusakova EY, Reva IV, Usov VV et al. An experience of dental implantation in patients with parodontal inflammatory diseases with local immune homeostasis control. Fundamental Researches. 2013; 5 (1): 129-134.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Kozlov SV, Remizova AA, Goncharov SO, Balayan MS. Deffered and immediate implantation in patients with metabolical syndrome. Parodontology. 2014; 19 (3): 57-62.</mixed-citation><mixed-citation xml:lang="en">Kozlov SV, Remizova AA, Goncharov SO, Balayan MS. Deffered and immediate implantation in patients with metabolical syndrome. Parodontology. 2014; 19 (3): 57-62.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Shokirov MN, Holnazarov BM, Bobiev GM, Hokirov MM, Hushvaktov DI, Hodzhaeva AM. Et al. Dental implantation in patients with diabetes mellitus with Timogar immunemodulator treatment. Tadzhikistan Science Academy news. Physics, mathematics, chemistry, geology and technical science unit. 2009; 1: 72-77.</mixed-citation><mixed-citation xml:lang="en">Shokirov MN, Holnazarov BM, Bobiev GM, Hokirov MM, Hushvaktov DI, Hodzhaeva AM. Et al. Dental implantation in patients with diabetes mellitus with Timogar immunemodulator treatment. Tadzhikistan Science Academy news. Physics, mathematics, chemistry, geology and technical science unit. 2009; 1: 72-77.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Saleeva GT. Features of osteointegration of dental implants in experimental diabetes mellitus. Thesis. Kazan, 1996: 19.</mixed-citation><mixed-citation xml:lang="en">Saleeva GT. Features of osteointegration of dental implants in experimental diabetes mellitus. Thesis. Kazan, 1996: 19.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">McCracken MS, Aponte-Wesson R, Chavali R, Lemons JE. Bone associated with implants in diabetic and insulin-treated rats. Clin Oral Implants Res 2006; 17: 495-500.</mixed-citation><mixed-citation xml:lang="en">McCracken MS, Aponte-Wesson R, Chavali R, Lemons JE. Bone associated with implants in diabetic and insulin-treated rats. Clin Oral Implants Res 2006; 17: 495-500.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Nevins ML, Karimbux NY, Weber HP, Giannobile WV, Fiorellini JP. Wound healing in endosseous implants in experimental diabetes. Int J Oral Maxillofac Implants 1998; 13: 620-629.</mixed-citation><mixed-citation xml:lang="en">Nevins ML, Karimbux NY, Weber HP, Giannobile WV, Fiorellini JP. Wound healing in endosseous implants in experimental diabetes. Int J Oral Maxillofac Implants 1998; 13: 620-629.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Bugea C, Luongo R, Di Iorio D, Cocchetto R, Celletti R. Bone contact around osseointegrated implants: Histologic analysis of a dual acid etched surface implant in a diabetic patient. Int J Periodontics Restorative Dent 2008; 28: 145-151.</mixed-citation><mixed-citation xml:lang="en">Bugea C, Luongo R, Di Iorio D, Cocchetto R, Celletti R. Bone contact around osseointegrated implants: Histologic analysis of a dual acid etched surface implant in a diabetic patient. Int J Periodontics Restorative Dent 2008; 28: 145-151.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Park JB. Bone healing at a failed implant site in a type II diabetic patient: Clinical and histologic evaluations: A case report. J Oral Implantol 2007; 33: 28-32.</mixed-citation><mixed-citation xml:lang="en">Park JB. Bone healing at a failed implant site in a type II diabetic patient: Clinical and histologic evaluations: A case report. J Oral Implantol 2007; 33: 28-32.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Turkyilmaz I. One-year clinical outcome of dental implants placed in patients with type 2 diabetes mellitus: A case. Implant Dent 2010; 19: 323-329.</mixed-citation><mixed-citation xml:lang="en">Turkyilmaz I. One-year clinical outcome of dental implants placed in patients with type 2 diabetes mellitus: A case. Implant Dent 2010; 19: 323-329.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Oates TW, Dowell S, Robinson M, McMahan CA. Glycemic control and implant stabilization in type 2 diabetes mellitus. J Dent Res 2009; 88: 367-371.</mixed-citation><mixed-citation xml:lang="en">Oates TW, Dowell S, Robinson M, McMahan CA. Glycemic control and implant stabilization in type 2 diabetes mellitus. J Dent Res 2009; 88: 367-371.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Loo WT, Jin LJ, Cheung MN, Wang M. The impact of diabetes on the success of dental implants and periodontal healing. Afr J Biotechnol 2009; 8: 122-127.</mixed-citation><mixed-citation xml:lang="en">Loo WT, Jin LJ, Cheung MN, Wang M. The impact of diabetes on the success of dental implants and periodontal healing. Afr J Biotechnol 2009; 8: 122-127.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Dowell S, Oates TW, Robinson M. Implant success in people with type 2 diabetes mellitus with varying glycemic control. J Am Dent Assoc 2007; 138: 355-361.</mixed-citation><mixed-citation xml:lang="en">Dowell S, Oates TW, Robinson M. Implant success in people with type 2 diabetes mellitus with varying glycemic control. J Am Dent Assoc 2007; 138: 355-361.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Balshi SF, Wolfinger GJ, Balshi TJ. An examination of immediately loaded dental implant stability in the diabetic patient using resonance frequency analysis (RFA). Quintessence Int 2007; 38: 271-279.</mixed-citation><mixed-citation xml:lang="en">Balshi SF, Wolfinger GJ, Balshi TJ. An examination of immediately loaded dental implant stability in the diabetic patient using resonance frequency analysis (RFA). Quintessence Int 2007; 38: 271-279.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Accursi GE. Treatment outcomes with osseointegrated Branemark implants in diabetic patients: A retrospective study [thesis]. Toronto (ON): University of Toronto; 2000; 127.</mixed-citation><mixed-citation xml:lang="en">Accursi GE. Treatment outcomes with osseointegrated Branemark implants in diabetic patients: A retrospective study [thesis]. Toronto (ON): University of Toronto; 2000; 127.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Balshi TJ, Wolfinger GJ. Dental implants in the diabetic patient: A retrospective study. Implant Dent 1999; 8: 355-359.</mixed-citation><mixed-citation xml:lang="en">Balshi TJ, Wolfinger GJ. Dental implants in the diabetic patient: A retrospective study. Implant Dent 1999; 8: 355-359.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Fazard P, Andersson L, Nyberg J. Dental implant treatment in diabetic patients. Implant Dent 2002; 11: 262-267.</mixed-citation><mixed-citation xml:lang="en">Fazard P, Andersson L, Nyberg J. Dental implant treatment in diabetic patients. Implant Dent 2002; 11: 262-267.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Morris HF, Ochi S, Winkler S. Implant survival in patients with type 2 diabetes: Placement to 36 month. Ann Periodontol 2000; 5: 157-163</mixed-citation><mixed-citation xml:lang="en">Morris HF, Ochi S, Winkler S. Implant survival in patients with type 2 diabetes: Placement to 36 month. Ann Periodontol 2000; 5: 157-163</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Fiorellini JP, Chen PK, Nevins M, Nevins ML. A retrospective study of Dental implants in diabetic patients. Int J Periodontics Restorative Dent 2000; 20: 366-373.</mixed-citation><mixed-citation xml:lang="en">Fiorellini JP, Chen PK, Nevins M, Nevins ML. A retrospective study of Dental implants in diabetic patients. Int J Periodontics Restorative Dent 2000; 20: 366-373.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Moy PK, Mediana D, Shetty V, Aghloo TL. Dental implant failure rates and associated factors. Int J Oral Maxillofac Implants 2005; 20: 569-577.</mixed-citation><mixed-citation xml:lang="en">Moy PK, Mediana D, Shetty V, Aghloo TL. Dental implant failure rates and associated factors. Int J Oral Maxillofac Implants 2005; 20: 569-577.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Rajendra KD, Deepesh KG, Amit K S. Dental implant survival in diabetic patients; review and recommendations. National Journal of Maxillofacial Surgery 2013; 4:2: 142-150.</mixed-citation><mixed-citation xml:lang="en">Rajendra KD, Deepesh KG, Amit K S. Dental implant survival in diabetic patients; review and recommendations. National Journal of Maxillofacial Surgery 2013; 4:2: 142-150.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Misch CE. Contemporary implant dentistry Elsevier, 2008. - 616 с.</mixed-citation><mixed-citation xml:lang="en">Misch CE. Contemporary implant dentistry Elsevier, 2008. - 616 с.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
